3-Formylindole

3-Formylindole

SCHEMBL56373

O=Cc1c[nH]c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 1.00
IMPDH2 P12268 1/20 1.00
PIM1 P11309 1/20 0.59
PIM3 Q86V86 1/20 0.59
PIM2 Q9P1W9 1/20 0.59
HPGD P15428 3/20 0.58
HTT P42858 1/20 0.58
APP P05067 1/20 0.53
ALDH1A1 P00352 5/20 0.53
MAPT P10636 4/20 0.53
KMT2A Q03164 3/20 0.53
KDM4E B2RXH2 3/20 0.53
LMNA P02545 2/20 0.53
MEN1 O00255 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
NPC1 O15118 1/20 0.53
NFKB1 P19838 1/20 0.53
RAB9A P51151 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Formylindole SCHEMBL30782674 1.00 CYP2A6 (1.00) CYP2A6IMPDH2PIM1PIM3PIM2
3-Formylindole SCHEMBL38654556 1.00 CYP2A6 (1.00) CYP2A6IMPDH2PIM1PIM3PIM2
3-Formylindole SCHEMBL30786737 1.00 CYP2A6 (1.00) CYP2A6IMPDH2PIM1PIM3PIM2
3-Formylindole SCHEMBL23630272 0.98 CYP2A6 (0.96) CYP2A6IMPDH2PIM1PIM3PIM2
3-Formylindole SCHEMBL7432698 0.98 CYP2A6 (0.96) CYP2A6IMPDH2PIM1PIM3PIM2
3-Formylindole SCHEMBL27269605 0.98 CYP2A6 (0.96) CYP2A6IMPDH2PIM1PIM3PIM2
3-Formylindole SCHEMBL30234679 0.98 CYP2A6 (0.96) CYP2A6IMPDH2PIM1PIM3PIM2
3-Formylindole SCHEMBL27637265 0.98 CYP2A6 (0.96) CYP2A6IMPDH2PIM1PIM3PIM2
3-Formylindole SCHEMBL27868505 0.91 CYP2A6 (0.82) CYP2A6IMPDH2PIM1PIM3PIM2
3-Formylindole SCHEMBL28868299 0.89 CYP2A6 (0.79) CYP2A6IMPDH2PIM1PIM3PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6566 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121673522-B Low-density polyurethane foam material and preparation method and application thereof 厦门柏伦亚聚氨酯科技有限公司 2026-05-19 CN claimed
CN-122031539-A Pine bark polyphenol extract and preparation method and application thereof 北京农学院 2026-05-15 CN claimed
EP-4739326-A2 PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA SNIPR Biome ApS (DK) 2026-05-13 EP claimed
CN-121574836-A Chaetomium globosum, method for separating secondary metabolites thereof and application 广东药科大学 2026-02-27 CN claimed
CN-121574881-A Chironomum and application thereof 华中科技大学同济医学院附属同济医院 2026-02-27 CN claimed
CN-121577903-A Biomarker combination for acute respiratory distress syndrome prognosis evaluation and application thereof 中国人民解放军总医院第八医学中心 2026-02-27 CN claimed
US-20260053887-A1 Methods and Kits to Prevent And/Or Treat Cardiac Disorders UNIV IOWA RES FOUND (US) 2026-02-26 US claimed
US-20260014215-A1 COMPOSITIONS CONTAINING INDOLE-DERIVED METABOLITES AND METHODS OF USE THEREOF Imvela Corp. (US) 2026-01-15 US claimed
US-12491220-B2 Compositions containing indole-derived metabolites and methods of use thereof Imvela Corp. (US) 2025-12-09 US claimed
EP-4637758-A1 COMPOSITION FOR CARING FOR KERATIN MATERIALS, COMPRISING AT LEAST INDOLE-3-LACTIC ACID, INDOLE-3-CARBOXALDEHYDE, INDOLE-3-ACETIC ACID AND AN ADJUVANT, USES AND PROCESS IMPLEMENTING THE COMPOSITION L'OREAL (FR) 2025-10-29 EP claimed
US-4727060-A HYPOTENSIVE AGENTS CIBA-GEIGY CORPORATION (US) 1988-02-23 US claimed
US-4705864-A Aryl oxime derivatives of hydantoins THE STANDARD OIL COMPANY (US) 1987-11-10 US claimed
US-4681828-A Method of chemical electrographic image amplification using chemically active toner particles EASTMAN KODAK COMPANY (US) 1987-07-21 US claimed
EP-0185538-A2 The synthesis of indole alkaloids Kong, Yun Cheung, Dr. (HK) 1986-06-25 EP claimed
EP-0184550-A2 5-Amino-4-hydroxy valeryl amide derivatives CIBA-GEIGY AG (CH) 1986-06-11 EP claimed
US-4582903-A Synthesis of unsaturated hydantoins with an inexpensive catalyst STAUFFER CHEMICAL COMPANY (US) 1986-04-15 US claimed
EP-0053893-B1 DERIVATIVES OF CLAVULANIC ACID, THEIR PREPARATION AND THEIR USE BEECHAM GROUP PLC (GB) 1985-03-20 EP claimed
EP-0043752-B1 PYRANOINDOLE DERIVATIVE AND PROCESS FOR ITS PREPARATION SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. Société anonyme dite: (FR) 1984-06-13 EP claimed
US-4314058-A Indolins styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-02-02 US claimed
US-3980667-A Anti-arrhythmic 5-endo-substituted oxy-N-(aminoloweralkyl)bicycle [2.2.2.]oc BRISTOL-MYERS COMPANY (US) 1976-09-14 US claimed