Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.63 |
| ▸ | CA2 | P00918 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CHAT | P28329 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59702 | 0.89 | CA1 (0.69) | CA1CA2HTTMCL1ALDH1A1 | |
| Formaldehyde SCHEMBL28349296 | 0.88 | CA1 (0.68) | CA1CA2HTTMCL1ALDH1A1 | |
| Hydrogen Sulfide SCHEMBL29288363 | 0.87 | CA1 (0.67) | CA1CA2HTTMCL1ALDH1A1 | |
| SCHEMBL27788199 | 0.87 | CA1 (0.67) | CA1CA2HTTMCL1ALDH1A1 | |
| SCHEMBL27593533 | 0.87 | CA1 (0.67) | CA1CA2HTTMCL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL25405344 | 0.87 | CA1 (0.67) | CA1CA2HTTMCL1ALDH1A1 | |
| SCHEMBL28118590 | 0.87 | CA1 (0.67) | CA1CA2HTTMCL1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27660602 | 0.87 | CA1 (0.67) | CA1CA2HTTMCL1ALDH1A1 | |
| Formic Acid SCHEMBL28913011 | 0.82 | CA1 (0.61) | CA1CA2HTTMCL1ALDH1A1 | |
| SCHEMBL28397671 | 0.80 | TSHR (0.50) | CA1CA2HTTMCL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256208-B2 | Monocyclic N-Aryl hydantoin modulators of androgen receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-14 | — | — | US | disclosed |
| US-20050153968-A1 | Monocyclic N-aryl hydantoin modulators of androgen receptor function | BRISTOL-MYERS SQUIBB COMPANY | 2005-07-14 | — | — | US | disclosed |
| WO-2005049580-A1 | MONOCYCLIC N-ARYL HYDANTOIN MODULATORS OF ANDROGEN RECEPTOR FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153968-A1 | Monocyclic N-aryl hydantoin modulators of androgen receptor function | AR, NR5A1, CYP19A1 | CA1 3865/4885CA2 2457/4885HTT 664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.