Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KISS1R | Q969F8 | 8/20 | 0.38 |
| ▸ | BMX | P51813 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4703800 | 0.92 | MAPT (0.44) | MAPTMEN1LMNAKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL5643385 | 0.91 | MAPT (0.43) | MAPTMEN1LMNAKMT2AKDM4E | |
| SCHEMBL4699803 | 0.86 | MAPT (0.42) | MAPTMEN1LMNAKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL5642754 | 0.85 | MAPT (0.42) | MAPTMEN1LMNAKMT2AKDM4E | |
| SCHEMBL4699977 | 0.84 | MAPT (0.39) | MAPTMEN1LMNAKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL5645088 | 0.84 | MAPT (0.39) | MAPTMEN1LMNAKMT2AKDM4E | |
| SCHEMBL4699269 | 0.83 | MAPT (0.38) | MAPTMEN1LMNAKMT2AKDM4E | |
| SCHEMBL4703491 | 0.83 | MAPT (0.45) | MAPTMEN1LMNAKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL5643980 | 0.82 | MAPT (0.38) | MAPTMEN1LMNAKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL5643841 | 0.82 | MAPT (0.44) | MAPTMEN1LMNAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192975-B2 | Arylimidazole derivatives, preparation and therapeutic used thereof | SOCIETE DE CONSEILS DE RECHERCHES ET D''APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2007-03-20 | — | — | US | claimed |