SCHEMBL5644402

SCHEMBL5644402

ClC(Cl)n1cccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2325760 0.72
SCHEMBL5642063 0.72
SCHEMBL28858796 0.65
SCHEMBL2816337 0.65
SCHEMBL5640922 0.61
SCHEMBL5639791 0.61
SCHEMBL1091555 0.61
SCHEMBL1897285 0.61
SCHEMBL536125 0.60
SCHEMBL30521601 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112292436-A Extruded PET film with light stable dyes for color conversion 巴斯夫欧洲公司 2021-01-29 CN disclosed
CN-108586506-A A kind of glimmering vinyl coumarin derivative of fluorine boron and its synthetic method and application 山西大学 2018-09-28 CN disclosed
CN-105753863-B Oxo-dihydroimidazopyridine compound and application thereof 东莞市真兴贝特医药技术有限公司 2018-07-31 CN disclosed
CN-108350018-A The manufacturing method of oligonucleotides 日产化学工业株式会社 2018-07-31 CN disclosed
CN-107108694-A Targeted delivery of tertiary amine-containing drug substances 西雅图基因公司 2017-08-29 CN disclosed
CN-106749365-A A kind of H2S detection reagents and its synthetic method and application 山西大学 2017-05-31 CN disclosed
CN-106674076-A Near-infrared H2S detection reagent and synthesis method and application thereof 山西大学 2017-05-17 CN disclosed
CN-103787927-B Deliver method, compound, compositionss and the carrier of 3 amino 1 propane sulfonic acid BHI有限合资公司 2017-03-01 CN disclosed
CN-101195672-B Method for producing olefin-copolymerization catalyst and method for producing olefin-copolymers SUMITOMO CHEMICAL CO 2011-07-06 CN disclosed
CN-101679365-A As the new pyrrole-2-carboxamides derivatives of glucokinase activators, their manufacture method and pharmaceutical application ADVINUS THERAPEUTICS PRIVATE L 2010-03-24 CN disclosed
EP-1341766-B1 IMIDAZOLONE DERIVATIVES FOR THE TREATMENT OF VIRAL DISEASES HOFFMANN LA ROCHE (CH) 2005-10-26 EP disclosed
US-20040192752-A1 Anti-HIV pyrazole derivatives DYMOCK BRIAN WILLIAM (GB) 2004-09-30 US disclosed
US-6699887-B2 ADMINISTERING A THERAPEUTICALLY EFFECTIVE AMOUNT OF A PYRRAZOLE SULFIDE OR ETHER COMPOUND TO TREAT THE HUMAN IMMUNODEFICIENCY VIRUS INFECTION HOFFMANN-LA ROCHE INC. 2004-03-02 US disclosed
EP-1341766-A1 IMIDAZOLONE DERIVATIVES FOR THE TREATMENT OF VIRAL DISEASES F. HOFFMANN-LA ROCHE AG (CH) 2003-09-10 EP disclosed
EP-1326843-A1 PYRAZOLE DERIVATIVES FOR THE TREATMENT OF VIRAL DISEASES F. Hoffmann-La Roche AG (CH) 2003-07-16 EP disclosed
US-6518293-B2 Inhibitors of the human immunodeficiency virus reverse transcriptase enzyme which is involved in viral replication. HOFFMANN-LA ROCHE INC. 2003-02-11 US disclosed
US-20030018197-A1 Anti-HIV pyrazole derivatives HOFFMANN-LA ROCHE INC. 2003-01-23 US disclosed
US-20020107272-A1 Anti-HIV imidazolone derivatives F. HOFFMANN-LA ROCHE AG (CH) 2002-08-08 US disclosed
WO-2002042279-A1 IMIDAZOLONE DERIVATIVES FOR THE TREATMENT OF VIRAL DISEASES F. HOFFMANN-LA ROCHE AG (CH) 2002-05-30 WO disclosed
WO-2002030907-A1 PYRAZOLE DERIVATIVES FOR THE TREATMENT OF VIRAL DISEASES F. HOFFMANN-LA ROCHE AG (CH) 2002-04-18 WO disclosed