Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5007752 | 0.92 | GFER (0.55) | GFERADORA1ADORA2AADORA2BKDM4E | |
| SCHEMBL5005304 | 0.91 | GFER (0.48) | GFERADORA1ADORA2AADORA2BKDM4E | |
| SCHEMBL5011968 | 0.91 | GFER (0.46) | GFERADORA1ADORA2AADORA2BKDM4E | |
| SCHEMBL5005306 | 0.89 | TDP1 (0.48) | GFERADORA1ADORA2AADORA2BKDM4E | |
| SCHEMBL5010645 | 0.88 | KMT2A (0.52) | GFERADORA1ADORA2AADORA2BKDM4E | |
| SCHEMBL5640287 | 0.88 | GFER (0.43) | GFERADORA1ADORA2AADORA2BKDM4E | |
| SCHEMBL5005348 | 0.86 | GFER (0.56) | GFERADORA1ADORA2AADORA2BKDM4E | |
| SCHEMBL5641025 | 0.86 | GFER (0.56) | GFERKDM4ERAB9ANPC1MAPT | |
| SCHEMBL5007723 | 0.85 | KMT2A (0.45) | GFERADORA1ADORA2AADORA2BKDM4E | |
| SCHEMBL5008503 | 0.84 | MAPT (0.51) | NPC1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265144-B2 | Anilinopyrazole derivatives useful for the treatment of diabetes | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-09-04 | — | — | US | disclosed |