SCHEMBL564459

SCHEMBL564459

C#CCOCCOCCOCCOCCOC

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
CA2 P00918 1/20 0.33
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL563670 1.00 TSHR (0.40) TSHRCA2MEN1ALDH1A1KMT2A
SCHEMBL10226156 1.00 TSHR (0.40) TSHRCA2MEN1ALDH1A1KMT2A
SCHEMBL18244712 1.00 TSHR (0.40) TSHRCA2MEN1ALDH1A1KMT2A
SCHEMBL8928 1.00 TSHR (0.40) TSHRCA2MEN1ALDH1A1KMT2A
SCHEMBL31115609 1.00 TSHR (0.40) TSHRCA2MEN1ALDH1A1KMT2A
SCHEMBL40199 1.00 TSHR (0.40) TSHRCA2MEN1ALDH1A1KMT2A
SCHEMBL1394152 0.97
SCHEMBL15803984 0.86 TSHR (0.48) TSHRMEN1ALDH1A1KMT2A
SCHEMBL12360400 0.86 TSHR (0.48) TSHRMEN1ALDH1A1KMT2A
SCHEMBL31324014 0.86 TSHR (0.48) TSHRMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122016947-A Click chemistry-based transformer oil acetylene degassing-free detection method and system 武汉豪迈光电科技有限公司 2026-05-12 CN disclosed
US-12084517-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells YALE UNIVERSITY (US) 2024-09-10 US disclosed
US-20240158430-A1 NOVEL COMPOUND OR SALT THEREOF, AND ANTITUMOR ACTIVATOR CONTAINING SAME AS ACTIVE INGREDIENT AKITA UNIVERSITY (JP) 2024-05-16 US disclosed
US-20240067756-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS UNIV YALE (US) 2024-02-29 US disclosed
WO-2024010810-A2 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF CIDARA THERAPEUTICS, INC. (US) 2024-01-11 WO disclosed
US-11725064-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells YALE UNIVERSITY (US) 2023-08-15 US disclosed
WO-2022190915-A1 NOVEL COMPOUND OR SALT THEREOF, AND ANTITUMOR ACTIVATOR CONTAINING SAME AS ACTIVE INGREDIENT 国立大学法人秋田大学 2022-09-15 WO disclosed
US-20220023428-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-01-27 US disclosed
US-11014992-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells YALE UNIVERSITY (US) 2021-05-25 US disclosed
US-20200354476-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS UNIV YALE (US) 2020-11-12 US disclosed
US-10703823-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells YALE UNIVERSITY (US) 2020-07-07 US disclosed
US-20190127487-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS YALE UNIVERSITY 2019-05-02 US disclosed
US-10066026-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells YALE UNIVERSITY (US) 2018-09-04 US disclosed
US-20160347863-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS YALE UNIVERSITY 2016-12-01 US disclosed
US-9296708-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells YALE UNIVERSITY (US) 2016-03-29 US disclosed
EP-2743267-B1 Dental materials based on polymerisable azides and alkenes IVOCLAR VIVADENT AG (LI) 2015-03-04 EP disclosed
US-8852630-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells YALE UNIVERSITY (US) 2014-10-07 US disclosed
EP-2743267-A1 Dental materials based on polymerisable azides and alkenes Ivoclar Vivadent AG (LI) 2014-06-18 EP disclosed
US-20120034295-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS YALE UNIVERSITY 2012-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11725064-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells BRDT, PAICS, KLK3 TSHR 4176/4885CA2 2364/4885MEN1 1313/4885
US-20120034295-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS BRDT, PAICS, KLK3 TSHR 4176/4885CA2 2364/4885MEN1 1313/4885
US-20240158430-A1 NOVEL COMPOUND OR SALT THEREOF, AND ANTITUMOR ACTIVATOR CONTAINING SAME AS ACTIVE INGREDIENT STAT3, STAT6, HDAC1 TSHR 4652/4885CA2 254/4885MEN1 1133/4885
US-20220023428-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS BRDT, PAICS, KLK3 TSHR 4176/4885CA2 2364/4885MEN1 1313/4885
US-20190127487-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS BRDT, PAICS, KLK3 TSHR 4176/4885CA2 2364/4885MEN1 1313/4885
US-20200354476-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS BRDT, PAICS, KLK3 TSHR 4176/4885CA2 2364/4885MEN1 1313/4885
US-20240067756-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS BRDT, PAICS, KLK3 TSHR 4176/4885CA2 2364/4885MEN1 1313/4885
US-11014992-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells BRDT, PAICS, KLK3 TSHR 4176/4885CA2 2364/4885MEN1 1313/4885
US-12084517-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells BRDT, PAICS, KLK3 TSHR 4176/4885CA2 2364/4885MEN1 1313/4885
US-10066026-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells BRDT, PAICS, KLK3 TSHR 4176/4885CA2 2364/4885MEN1 1313/4885
US-10703823-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells BRDT, PAICS, KLK3 TSHR 4176/4885CA2 2364/4885MEN1 1313/4885
US-20160347863-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS BRDT, PAICS, KLK3 TSHR 4176/4885CA2 2364/4885MEN1 1313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.