SCHEMBL564576

SCHEMBL564576

NC(Nc1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.48
DPP4 P27487 2/20 0.48
F2 P00734 1/20 0.48
LMNA P02545 3/20 0.42
CYP3A4 P08684 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
IDO1 P14902 1/20 0.42
CYP2C19 P33261 1/20 0.42
PTGS2 P35354 1/20 0.42
RECQL P46063 2/20 0.41
ALDH1A1 P00352 2/20 0.41
THRB P10828 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
ALOX12 P18054 1/20 0.41
ATM Q13315 1/20 0.41
HSD17B10 Q99714 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8790661 0.87 MAPT (0.50) TDP1DPP4F2LMNACYP3A4
SCHEMBL27791675 0.85 TDP1 (0.40) TDP1DPP4F2LMNACYP3A4
SCHEMBL27728688 0.85 IDO1 (0.46) TDP1LMNACYP1A2IDO1TSHR
SCHEMBL16603000 0.76 DPP4 (0.56) TDP1DPP4F2LMNACYP3A4
SCHEMBL18965406 0.76 TDP1 (0.48) TDP1DPP4F2LMNACYP3A4
SCHEMBL24727513 0.76 TDP1 (0.55) TDP1DPP4F2LMNACYP3A4
SCHEMBL16900469 0.76 DPP4 (0.55) DPP4F2LMNAALDH1A1TSHR
SCHEMBL14527693 0.76 TDP1 (0.55) TDP1DPP4F2LMNACYP3A4
SCHEMBL7187017 0.76 DPP4 (0.55) DPP4F2LMNAALDH1A1TSHR
SCHEMBL9718695 0.74 TDP1 (0.52) TDP1DPP4LMNACYP3A4IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025073928-A1 PROCESS FOR PREPARING MDA BASF SE (DE) 2025-04-10 WO claimed
CN-119684159-A Method for reducing content of hydrolytic chlorine in isocyanate 万华化学(福建)异氰酸酯有限公司 2025-03-25 CN claimed
CN-119390586-A Process for preparing aromatic polyamine mixtures 巴斯夫欧洲公司 2025-02-07 CN claimed
EP-2268713-B1 PROCESS FOR MAKING POLYAMINOPOLYPHENYL METHANES USING A MIXED SOLID ACID CATALYST SYSTEM DOW GLOBAL TECHNOLOGIES LLC (US) 2018-02-21 EP claimed
EP-1257522-B1 METHOD FOR PRODUCTION OF DIAMINODIPHENYLMETHANES BAYER MATERIALSCIENCE AG (DE) 2006-01-04 EP claimed
US-6100308-A COPOLYMERIZING A DI- OR POLYISOCYANATES WITH A POLYETHER POLYOLS BASED ON AROMATIC AMINES WITH CHAIN EXTENDERS AND/OR CROSSLINKERS IN THE PRESENCE OF BLOWING AGENTS TO FORM THE RIGID POLYETHERURETHANE FOAMS; USE AS INSULATION MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2000-08-08 US claimed
WO-2025073928-A1 PROCESS FOR PREPARING MDA BASF SE (DE) 2025-04-10 WO disclosed
CN-119684159-A Method for reducing content of hydrolytic chlorine in isocyanate 万华化学(福建)异氰酸酯有限公司 2025-03-25 CN disclosed
CN-119684159-A Method for reducing content of hydrolytic chlorine in isocyanate 万华化学(福建)异氰酸酯有限公司 2025-03-25 CN disclosed
CN-119390586-A Process for preparing aromatic polyamine mixtures 巴斯夫欧洲公司 2025-02-07 CN disclosed
US-20230028994-A1 HETEROGENEOUS SYNTHESIS OF METHYLENE DIANILINE BASF SE (DE) 2023-01-26 US disclosed
EP-4072726-A1 HETEROGENEOUS SYNTHESIS OF METHYLENE DIANILINE BASF SE (DE) 2022-10-19 EP disclosed
CN-110088078-B Process for producing di-and polyamines of the diphenylmethane series 科思创德国股份有限公司 2022-09-09 CN disclosed
EP-0109931-A2 Process for the preparation of polyaryl amines showing methylene bridges ELPROCHINE AG (CH) 1984-05-30 EP disclosed
EP-0078414-A1 Process for the preparation of diamines of the diphenylmethane series CHEMIE LINZ AKTIENGESELLSCHAFT (AT) 1983-05-11 EP disclosed
US-4319018-A IN ACID CATALYST MITSUI TOATSU CHEMICALS, INC. (JP) 1982-03-09 US disclosed
US-4186145-A Process for the hydrogenation of an aromatic amine and the supported ruthenium catalyst used in the process BAYER AKTIENGESELLSCHAFT (DE) 1980-01-29 US disclosed
US-4087459-A Process for the preparation of polyamines BAYER AKTIENGESELLSCHAFT (DT) 1978-05-02 US disclosed
US-4039581-A Process for the preparation of di(amino phenyl)methanes THE UPJOHN COMPANY (US) 1977-08-02 US disclosed
US-3993632-A PROPELLANT BINDER SHELL OIL COMPANY (US) 1976-11-23 US disclosed