Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.98 |
| ▸ | HTR2C | P28335 | 6/20 | 0.98 |
| ▸ | FAAH | O00519 | 7/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5651133 | 0.99 | MCHR1 (1.00) | MCHR1HTR2CFAAH | |
| SCHEMBL5646980 | 0.91 | MCHR1 (0.98) | MCHR1HTR2CFAAHTP53MAPT | |
| SCHEMBL5645048 | 0.90 | MCHR1 (1.00) | MCHR1HTR2CFAAH | |
| SCHEMBL5650636 | 0.90 | MCHR1 (1.00) | MCHR1HTR2CFAAHTP53MAPT | |
| SCHEMBL5651220 | 0.90 | MCHR1 (1.00) | MCHR1HTR2CFAAH | |
| SCHEMBL5649051 | 0.88 | MCHR1 (1.00) | MCHR1HTR2CFAAH | |
| SCHEMBL2925899 | 0.87 | MCHR1 (0.75) | MCHR1HTR2CFAAHTP53MAPT | |
| SCHEMBL2925998 | 0.86 | MCHR1 (0.77) | MCHR1HTR2CFAAHTP53MAPT | |
| SCHEMBL2928221 | 0.85 | MCHR1 (0.72) | MCHR1HTR2CFAAHTP53MAPT | |
| SCHEMBL2925581 | 0.84 | MCHR1 (0.73) | MCHR1HTR2CFAAHTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183415-B2 | Quinoline compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-7183415-B2 | Quinoline compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-7183415-B2 | Quinoline compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1447402-A1 | QUINOLINE COMPOUND | Takeda Chemical Industries, Ltd. (JP) | 2004-08-18 | — | — | EP | disclosed |