Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 13/20 | 0.79 |
| ▸ | HTR2C | P28335 | 9/20 | 0.79 |
| ▸ | F10 | P00742 | 1/20 | 0.55 |
| ▸ | ACKR3 | P25106 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5647773 | 0.91 | MCHR1 (0.79) | MCHR1HTR2CACKR3 | |
| SCHEMBL5648064 | 0.88 | MCHR1 (1.00) | MCHR1HTR2C | |
| SCHEMBL5647227 | 0.87 | MCHR1 (0.98) | MCHR1HTR2C | |
| SCHEMBL5644747 | 0.87 | MCHR1 (0.77) | MCHR1HTR2CACKR3 | |
| SCHEMBL5651358 | 0.85 | MCHR1 (0.72) | MCHR1HTR2CACKR3 | |
| SCHEMBL5650554 | 0.83 | MCHR1 (0.71) | MCHR1HTR2CACKR3 | |
| SCHEMBL6621201 | 0.81 | MCHR1 (0.84) | MCHR1HTR2C | |
| SCHEMBL5648304 | 0.81 | MCHR1 (1.00) | MCHR1HTR2C | |
| SCHEMBL5646506 | 0.80 | MCHR1 (0.80) | MCHR1HTR2C | |
| SCHEMBL5645500 | 0.80 | MCHR1 (0.98) | MCHR1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183415-B2 | Quinoline compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-7183415-B2 | Quinoline compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-7183415-B2 | Quinoline compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1447402-A1 | QUINOLINE COMPOUND | Takeda Chemical Industries, Ltd. (JP) | 2004-08-18 | — | — | EP | disclosed |