Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22530550 | 0.88 | NR1H4 (0.53) | NR1H4RAB9ANPC1HPGDNPSR1 | |
| SCHEMBL15299214 | 0.86 | NR1H4 (0.51) | NR1H4RAB9ANPC1AOC3HPGD | |
| SCHEMBL31375602 | 0.84 | NPC1 (0.54) | NR1H4RAB9ANPC1AOC3HPGD | |
| SCHEMBL5641740 | 0.82 | HDAC4 (0.57) | NR1H4RAB9ANPC1HDAC4HDAC6 | |
| SCHEMBL21889831 | 0.82 | AOC3 (0.50) | RAB9ANPC1AOC3HPGDNPSR1 | |
| SCHEMBL23917850 | 0.82 | NR1H4 (0.56) | NR1H4RAB9ANPC1AOC3KMT2A | |
| SCHEMBL6497959 | 0.82 | AOC3 (0.50) | RAB9ANPC1AOC3HPGDNPSR1 | |
| SCHEMBL77622 | 0.81 | NR1H4 (0.57) | NR1H4RAB9ANPC1AOC3MEN1 | |
| SCHEMBL31375480 | 0.81 | AOC3 (0.47) | RAB9ANPC1AOC3HPGDNPSR1 | |
| SCHEMBL14153764 | 0.81 | NPC1 (0.54) | RAB9ANPC1AOC3HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297797-B2 | Pyrrolines | BAYER CROPSCIENCE AG (DE) | 2007-11-20 | — | — | US | disclosed |
| US-20060142343-A1 | Pyrrolines | BAYER CROPSCIENCE AG (DE) | 2006-06-29 | — | — | US | disclosed |
| EP-1546144-A2 | DELTA1 PYRROLINES USED AS PESTICIDES | Bayer CropScience AG (DE) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031176-A2 | DELTA1 PYRROLINES USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2004-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142343-A1 | Pyrrolines | CHRM1, PRMT1, RRS1 | NR1H4 4220/4885RAB9A 8/4885NPC1 3694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.