Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.91 |
| ▸ | CNR1 | P21554 | 6/20 | 0.91 |
| ▸ | PPARG | P37231 | 2/20 | 0.68 |
| ▸ | PPARD | Q03181 | 2/20 | 0.68 |
| ▸ | PPARA | Q07869 | 2/20 | 0.68 |
| ▸ | FAAH | O00519 | 4/20 | 0.64 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL564921 | 1.00 | CNR2 (0.91) | CNR2CNR1PPARGPPARDPPARA | |
| SCHEMBL564920 | 1.00 | CNR2 (0.91) | CNR2CNR1PPARGPPARDPPARA | |
| SCHEMBL22498742 | 0.99 | CNR2 (0.94) | CNR2CNR1PPARGPPARDPPARA | |
| SCHEMBL22498743 | 0.99 | CNR2 (0.94) | CNR2CNR1PPARGPPARDPPARA | |
| SCHEMBL27101572 | 0.98 | CNR2 (0.94) | CNR2CNR1PPARGPPARDPPARA | |
| SCHEMBL22397862 | 0.97 | CNR2 (0.97) | CNR2CNR1PPARGPPARDPPARA | |
| SCHEMBL20959755 | 0.97 | CNR2 (0.97) | CNR2CNR1PPARGPPARDPPARA | |
| SCHEMBL31231143 | 0.97 | CNR2 (0.97) | CNR2CNR1PPARGPPARDPPARA | |
| SCHEMBL31231145 | 0.97 | CNR2 (0.97) | CNR2CNR1PPARGPPARDPPARA | |
| SCHEMBL28274714 | 0.97 | CNR2 (0.97) | CNR2CNR1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035855-A1 | METHOD OF NETWORK-BASED IDENTIFICATION FOR DRUG ACTION AND/OR SYNERGY EFFECT OF MEDICINE COMBINATION | TSINGHUA UNIVERSITY | 2012-02-09 | — | — | US | disclosed |
| EP-2369493-A1 | GENE NETWORK-BASED METHOD FOR CONFIRMING DRUG ACTION | Tsinghua University (CN) | 2011-09-28 | — | — | EP | disclosed |