Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5651353 | 0.92 | KDR (1.00) | KDREGFR | |
| SCHEMBL5647364 | 0.88 | KDR (0.85) | KDREGFR | |
| SCHEMBL5651836 | 0.88 | KDR (1.00) | KDREGFR | |
| SCHEMBL5650552 | 0.87 | KDR (1.00) | KDREGFR | |
| SCHEMBL5650380 | 0.87 | KDR (0.86) | KDREGFR | |
| SCHEMBL5651796 | 0.86 | KDR (0.81) | KDREGFR | |
| SCHEMBL5647584 | 0.86 | KDR (1.00) | KDR | |
| SCHEMBL5651217 | 0.85 | KDR (0.82) | KDREGFR | |
| SCHEMBL5650536 | 0.85 | KDR (0.82) | KDREGFR | |
| SCHEMBL5654134 | 0.85 | KDR (0.95) | KDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299092-A1 | Quinone Substituted Quinazoline and Quinoline Kinase Inhibitors | WYETH (US) | 2007-12-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299092-A1 | Quinone Substituted Quinazoline and Quinoline Kinase Inhibitors | KDR, FLT1, FLT4 | KDR 1/4885EGFR 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.