Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.68 |
| ▸ | CNR1 | P21554 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5624373 | 0.82 | CNR2 (0.68) | CNR2CNR1MAPTALDH1A1TP53 | |
| SCHEMBL5624009 | 0.80 | CNR2 (1.00) | CNR2CNR1MAPTTP53SMN1; SMN2 | |
| SCHEMBL5793824 | 0.80 | CNR2 (0.70) | CNR2CNR1MAPTALDH1A1TP53 | |
| SCHEMBL29717171 | 0.79 | CNR2 (0.73) | CNR2CNR1MAPTALDH1A1TP53 | |
| SCHEMBL5625255 | 0.79 | CNR2 (0.81) | CNR2CNR1MAPTALDH1A1TP53 | |
| SCHEMBL5623445 | 0.77 | CNR2 (1.00) | CNR2CNR1MAPTALDH1A1TP53 | |
| SCHEMBL5651438 | 0.76 | CNR2 (0.67) | CNR2CNR1MAPTALDH1A1TP53 | |
| SCHEMBL4252422 | 0.75 | SMN1; SMN2 (0.77) | CNR2CNR1MAPTALDH1A1TP53 | |
| SCHEMBL5623000 | 0.75 | CNR2 (1.00) | CNR2CNR1MAPTTP53NPC1 | |
| SCHEMBL4258322 | 0.75 | SMN1; SMN2 (0.82) | CNR2CNR1MAPTALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297796-B2 | Sulfamoyl benzamide derivatives and methods of their use | ADOLOR CORPORATION (US) | 2007-11-20 | — | — | US | disclosed |