Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4972142 | 1.00 | MAOB (0.37) | MAOBKDM1A | |
| SCHEMBL4972606 | 0.81 | MAOB (0.37) | MAOB | |
| SCHEMBL4971432 | 0.81 | CYP3A4 (0.37) | KDM1A | |
| SCHEMBL4971437 | 0.81 | CYP3A4 (0.37) | KDM1A | |
| SCHEMBL4968605 | 0.81 | SLC6A2 (0.38) | — | |
| SCHEMBL4968601 | 0.81 | SLC6A2 (0.38) | — | |
| SCHEMBL5654186 | 0.81 | MAOB (0.37) | MAOB | |
| SCHEMBL8647185 | 0.81 | SLC6A2 (0.38) | MAOBKDM1A | |
| SCHEMBL5651945 | 0.81 | TSHR (0.50) | MAOB | |
| SCHEMBL1515349 | 0.81 | TSHR (0.50) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | MEMORY PHARMACEUTICALS CORPORATION | 2007-11-15 | — | — | US | claimed |
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | MEMORY PHARMACEUTICALS CORPORATION | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | PDE7A, PDE10A, PDE7B | MAOB 173/4885KDM1A 1587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.