Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK1 | Q7L7X3 | 5/20 | 1.00 |
| ▸ | TAOK3 | Q9H2K8 | 4/20 | 1.00 |
| ▸ | EPHX2 | P34913 | 14/20 | 0.64 |
| ▸ | PPARG | P37231 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31458328 | 1.00 | TAOK1 (1.00) | TAOK1TAOK3EPHX2PPARGALDH1A1 | |
| SCHEMBL5652402 | 0.84 | TAOK1 (1.00) | TAOK1TAOK3EPHX2PPARGALDH1A1 | |
| SCHEMBL31458332 | 0.84 | TAOK1 (1.00) | TAOK1TAOK3EPHX2PPARGALDH1A1 | |
| SCHEMBL14422176 | 0.81 | TAOK1 (0.73) | TAOK1TAOK3EPHX2ALDH1A1 | |
| SCHEMBL21773985 | 0.78 | TAOK1 (0.64) | TAOK1TAOK3EPHX2PPARG | |
| SCHEMBL13754030 | 0.76 | TAOK1 (0.60) | TAOK1TAOK3ALDH1A1 | |
| SCHEMBL13059390 | 0.75 | TAOK1 (0.58) | TAOK1TAOK3EPHX2PPARG | |
| SCHEMBL5643051 | 0.75 | EPHX2 (0.79) | TAOK1TAOK3EPHX2PPARGALDH1A1 | |
| SCHEMBL5654217 | 0.74 | TAOK1 (0.63) | TAOK1TAOK3 | |
| Hydrochloric Acid SCHEMBL17687150 | 0.74 | TAOK1 (0.57) | TAOK1TAOK3EPHX2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | claimed |
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | TAOK1, TAOK3, MAP3K6 | TAOK1 1/4885TAOK3 2/4885EPHX2 3128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.