Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 7/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687873 | 0.79 | SLC2A1 (0.49) | KCNH2 | |
| SCHEMBL13145818 | 0.79 | SLC2A1 (0.49) | KCNH2 | |
| SCHEMBL5652545 | 0.79 | CYP2D6 (0.40) | KCNH2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL5441479 | 0.73 | KCNH2 (0.40) | KCNH2MCHR1NPSR1MEN1ALDH1A1 | |
| SCHEMBL5441471 | 0.73 | KCNH2 (0.40) | KCNH2MCHR1NPSR1MEN1ALDH1A1 | |
| SCHEMBL14372290 | 0.73 | KCNH2 (0.45) | KCNH2MCHR1NPSR1CNR1KDM4E | |
| SCHEMBL3700635 | 0.72 | SLC2A1 (0.45) | KCNH2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL3700630 | 0.72 | SLC2A1 (0.45) | KCNH2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL6688480 | 0.69 | KDM4E (0.40) | KCNH2CCR8KDM4EMEN1ALDH1A1 | |
| SCHEMBL3688295 | 0.69 | KCNH2 (0.47) | KCNH2KDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223776-B2 | Compounds with anti-bacterial activity | MORPHOCHEM AG (DE) | 2007-05-29 | — | — | US | disclosed |
| US-20060040949-A1 | Novel compounds with antibacterial activity | MORPHOCHEM AG | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040949-A1 | Novel compounds with antibacterial activity | MRPL21, Q6ZSR9, MRPL19 | KCNH2 2411/4885CCR8 3798/4885MCHR1 4271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.