Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 6/20 | 0.74 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.59 |
| ▸ | CDK8 | P49336 | 11/20 | 0.55 |
| ▸ | CDK19 | Q9BWU1 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CHUK | O15111 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4659211 | 0.85 | IKBKB (1.00) | IKBKBLIMK1CDK8CDK19ALDH1A1 | |
| SCHEMBL4657885 | 0.84 | IKBKB (0.70) | IKBKBLIMK1CDK8CDK19ALDH1A1 | |
| SCHEMBL4656539 | 0.83 | IKBKB (1.00) | IKBKBLIMK1CDK8CDK19ALDH1A1 | |
| SCHEMBL4658241 | 0.82 | IKBKB (1.00) | IKBKBLIMK1CDK8CDK19ALDH1A1 | |
| SCHEMBL4658024 | 0.79 | IKBKB (0.74) | IKBKBLIMK1CDK8CDK19ALDH1A1 | |
| SCHEMBL4657097 | 0.78 | IKBKB (0.72) | IKBKBLIMK1CDK8CDK19ALDH1A1 | |
| SCHEMBL4657771 | 0.78 | IKBKB (0.65) | IKBKBLIMK1CDK8CDK19ALDH1A1 | |
| SCHEMBL4656880 | 0.78 | IKBKB (0.64) | IKBKBLIMK1CDK8CDK19ALDH1A1 | |
| SCHEMBL16071478 | 0.77 | LIMK1 (0.72) | IKBKBLIMK1CDK8CDK19ALDH1A1 | |
| SCHEMBL5231314 | 0.76 | LIMK1 (0.70) | IKBKBLIMK1CDK8CDK19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | SANKYO COMPANY, LIMITED (JP) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | RASGRP1, NRAS, HRH3 | IKBKB 1715/4885LIMK1 3044/4885CDK8 2017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.