Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.65 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.58 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.58 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22618152 | 0.98 | ESR1 (0.68) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL22414159 | 0.98 | ESR1 (0.68) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL25769016 | 0.95 | ESR2 (0.72) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL10041513 | 0.95 | ESR2 (0.71) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL16692234 | 0.95 | ESR2 (0.71) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL14160911 | 0.93 | ESR1 (0.73) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL804992 | 0.93 | ESR2 (0.73) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL17177944 | 0.93 | ESR1 (0.57) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL64508 | 0.91 | ESR2 (0.66) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL29351258 | 0.91 | ESR2 (0.66) | ESR1ESR2GRIA1CACNG8CACNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7232619-B2 | Pyrene derivative, light emitting element, and light emitting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2007-06-19 | — | — | US | disclosed |
| US-20050079385-A1 | Pyrene derivative, light emitting element, and light emitting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2005-04-14 | — | — | US | disclosed |