Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 12/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1332408 | 0.91 | ADORA1 (0.66) | ADORA1ADORA2BADORA2AADORA3TSHR | |
| Hydrochloric Acid SCHEMBL1332578 | 0.90 | ADORA1 (0.65) | ADORA1ADORA2BADORA2AADORA3TSHR | |
| SCHEMBL1332532 | 0.90 | ADORA1 (0.65) | ADORA1ADORA2BADORA2AADORA3KMT2A | |
| SCHEMBL1332766 | 0.89 | ADORA1 (0.63) | ADORA1ADORA2BADORA2AADORA3KMT2A | |
| SCHEMBL4176173 | 0.88 | ADORA1 (0.62) | ADORA1ADORA2BADORA2AADORA3KMT2A | |
| SCHEMBL1333086 | 0.88 | ADORA1 (0.64) | ADORA1ADORA2BADORA2AADORA3KMT2A | |
| SCHEMBL1332444 | 0.87 | ADORA1 (0.62) | ADORA1ADORA2BADORA2AADORA3KMT2A | |
| SCHEMBL1334671 | 0.86 | ADORA1 (0.60) | ADORA1ADORA2BADORA2AADORA3KMT2A | |
| SCHEMBL1333191 | 0.86 | ADORA1 (0.62) | ADORA1ADORA2BADORA2AADORA3TSHR | |
| SCHEMBL1334308 | 0.86 | ADORA1 (0.57) | ADORA1ADORA2BADORA2AADORA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247639-B2 | A1 adenosine receptor antagonists | ENDACEA, INC. (US) | 2007-07-24 | — | — | US | claimed |