Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | VCP | P55072 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | PNP | P00491 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | EDNRA | P25101 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | HBB | P68871 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | HPRT1 | P00492 | 11/20 | 0.55 |
| ▸ | TK1 | P04183 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29325413 | 1.00 | BLM (0.59) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL8630516 | 0.90 | MEN1 (0.59) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL25611139 | 0.88 | PNP (0.53) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9827056 | 0.88 | BLM (0.53) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL8990304 | 0.87 | HPRT1 (0.62) | PNPHPRT1 | |
| SCHEMBL9385909 | 0.87 | HPRT1 (0.62) | PNPHPRT1 | |
| SCHEMBL5168886 | 0.86 | MEN1 (0.57) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL8540040 | 0.85 | BLM (0.58) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL27361069 | 0.85 | BLM (0.62) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL27361153 | 0.85 | BLM (0.62) | BLMMEN1ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060121091-A1 | Cellular uptake of bioactive agents | AESGEN, INC. | 2006-06-08 | — | — | US | disclosed |
| US-7041651-B2 | Cellular uptake of bioactive agents | AESGEN, INC. (US) | 2006-05-09 | — | — | US | disclosed |
| WO-2005110046-A2 | METHOD OF ENHANCING UPTAKE OF KERATINOCYTE GROWTH FACTOR | AESGEN, INC. (US) | 2005-11-24 | — | — | WO | disclosed |
| US-20040176319-A1 | Cellular uptake of bioactive agents | AESGEN, INC. | 2004-09-09 | — | — | US | disclosed |
| US-6734170-B2 | METABOLISM DISEASES; MIXTURE OF CARBOHYDRATE, AMINO ACIDS; ADJUST ABSORPTION | AESGAN, INC. | 2004-05-11 | — | — | US | disclosed |
| US-20020147156-A1 | Cellular uptake of bioactive agents | EISAI INC. | 2002-10-10 | — | — | US | disclosed |
| EP-1206283-A2 | IMPROVED CELLULAR UPTAKE OF BIOACTIVE AGENTS | Aesgen, Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2000069470-A2 | IMPROVED CELLULAR UPTAKE OF BIOACTIVE AGENTS | AESGEN, INC. (US) | 2000-11-23 | — | — | WO | disclosed |
| US-5994321-A | Antiviral guanine analogs | ARONEX PHARMACEUTICALS, INC. (US) | 1999-11-30 | — | — | US | disclosed |
| US-5446045-A | Viricides for treating AIDS, viral diseases | TRIPLEX PHARMACEUTICAL CORPORATION | 1995-08-29 | — | — | US | disclosed |