2-Nitrobenzaldehyde

2-Nitrobenzaldehyde

SCHEMBL5654

O=Cc1ccccc1[N+](=O)[O-]

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.66
MAPT P10636 2/20 0.56
CA12 O43570 1/20 0.53
SOS1 Q07889 1/20 0.53
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
TDP1 Q9NUW8 2/20 0.52
LMNA P02545 1/20 0.52
THRB P10828 1/20 0.52
BLM P54132 1/20 0.52
XDH P47989 2/20 0.51
NPSR1 Q6W5P4 1/20 0.51
MAOB P27338 1/20 0.51
HSD17B10 Q99714 1/20 0.50
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
KDM4E B2RXH2 1/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Nitrobenzaldehyde SCHEMBL29672618 1.00 ERN1 (0.66) ERN1MAPTCA12SOS1MEN1
2-Nitrobenzaldehyde SCHEMBL9323445 0.98 ERN1 (0.63) ERN1MAPTCA12SOS1MEN1
2-Nitrobenzaldehyde SCHEMBL27794898 0.98 ERN1 (0.63) ERN1MAPTCA12SOS1MEN1
2-Nitrobenzaldehyde SCHEMBL28981617 0.98 ERN1 (0.63) ERN1MAPTCA12SOS1MEN1
2-Nitrobenzaldehyde SCHEMBL28865451 0.98 ERN1 (0.63) ERN1MAPTCA12SOS1MEN1
2-Nitrobenzaldehyde SCHEMBL9812419 0.96 ERN1 (0.61) ERN1MAPTCA12SOS1MEN1
2-Nitrobenzaldehyde SCHEMBL27303251 0.96 ERN1 (0.61) ERN1MAPTCA12SOS1MEN1
2-Nitrobenzaldehyde SCHEMBL28121927 0.94 ERN1 (0.65) ERN1MAPTCA12SOS1MEN1
2-Nitrobenzaldehyde SCHEMBL3323403 0.94 ERN1 (0.59) ERN1MAPTCA12SOS1MEN1
2-Nitrobenzaldehyde SCHEMBL11730170 0.92 ERN1 (0.58) ERN1MAPTCA12SOS1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11875 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447329-B Method for preparing nitrobenzaldehyde by direct oxidation of nitrotoluene INSTITUTE OF COAL CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2026-05-26 CN claimed
CN-118005516-B Spinel structure Cu0.5Co0.5Al2O4Method for preparing o-nitrobenzaldehyde by catalysis of catalyst 常州大学 2026-05-15 CN claimed
US-12624144-B2 Method for preparing hollow covalent organic framework materials ZHEJIANG UNIVERSITY (CN) 2026-05-12 US claimed
CN-121574130-A Synthesis method of pyrazolo [1,2-b ] phthalazine-5, 10-dione derivative as drug intermediate and catalytic system for synthesis 南京苏亦欣医药科技有限公司 2026-02-27 CN claimed
US-20250215467-A1 L-THREONINE TRANSALDOLASES AND USES THEREOF UNIVERSITY OF DELAWARE (US) 2025-07-03 US claimed
CN-120192231-A Copper-based complex Cu (dppf) (BH)4) Application in nucleophilic addition reaction of arylboronic acid 安徽大学 2025-06-24 CN claimed
CN-119798054-B Alkyl functionalized cyclo-resveratrol hydrocarbon, preparation method thereof, capillary gas chromatographic column and application 洛阳师范学院 2025-06-13 CN claimed
CN-116333007-B Click chemistry-based light-responsive annular RNA synthesis method and application thereof 中国科学院化学研究所 2025-06-03 CN claimed
US-20250171410-A1 METHOD FOR FORMING A SCHIFF BASE WITH CATALYTIC SUPER-PARAMAGNETIC IRON OXIDE NANOPARTICLES IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2025-05-29 US claimed
CN-120044147-A Purifying and detecting method for chitosan composite filler of nitrofuran metabolites in aquatic products 中国水产科学研究院 2025-05-27 CN claimed
EP-0003981-B1 PROCESS FOR THE PREPARATION OF 2-NITROBENZALDEHYDE BAYER AG (DE) 1981-01-07 EP claimed
US-4213920-A Process for the production of substituted benzaldehydes CIBA-GEIGY CORPORATION (US) 1980-07-22 US claimed
US-4203928-A Process for the preparation of 2-nitrobenzaldehyde BAYER AKTIENGESELLSCHAFT (DE) 1980-05-20 US claimed
EP-0003981-A1 Process for the preparation of 2-nitrobenzaldehyde BAYER AG (DE) 1979-09-19 EP claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed
US-4129554-A PICRIC ACID, QUINONE, CHLORANIL, CYANOACETATE ESTER HITACHI CHEMICAL CO., LTD. (JP) 1978-12-12 US claimed
US-4020059-A Process for preparing tertiary amines NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JA) 1977-04-26 US claimed
US-4013639-A PREPARATION OF ASYMMETRIC IMINODIBENZYL COMPOUNDS Kitamura, Eiichi (JA) 1977-03-22 US claimed
US-3996289-A Process for the preparation of 2-nitrobenzaldehyde BAYER AKTIENGESELLSCHAFT (DT) 1976-12-07 US claimed
US-3951993-A HYPOTENSIVE, CORONARY VESSEL DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-20 US claimed