Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.71 |
| ▸ | PPARA | Q07869 | 9/20 | 0.71 |
| ▸ | PPARG | P37231 | 5/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655360 | 0.91 | PPARD (0.71) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL14573039 | 0.91 | PPARD (0.59) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5656813 | 0.87 | PPARD (0.76) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5697537 | 0.85 | PPARD (0.71) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5656255 | 0.83 | PPARD (1.00) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5656300 | 0.83 | PPARD (0.81) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6236634 | 0.83 | PPARD (1.00) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5655979 | 0.82 | PPARD (0.89) | PPARDPPARAPPARGFFAR1 | |
| Gw501516 SCHEMBL68714 | 0.82 | PPARD (1.00) | PPARDPPARAPPARG | |
| Gw501516 SCHEMBL29356729 | 0.82 | PPARD (1.00) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196107-B2 | Thia-and oxazoles and their use as ppars activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-27 | — | — | US | disclosed |
| US-7196107-B2 | Thia-and oxazoles and their use as ppars activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-27 | — | — | US | disclosed |
| US-7196107-B2 | Thia-and oxazoles and their use as ppars activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-27 | — | — | US | disclosed |
| US-20040102493-A1 | Thia-and oxazoles and their use as ppars activators | SMITHKLINE BEECHAM CORPORATION | 2004-05-27 | — | — | US | disclosed |
| EP-1343772-A1 | THIA- AND OXAZOLES AND THEIR USE AS PPARS ACTIVATORS | GLAXO GROUP LIMITED (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002050048-A1 | THIA- AND OXAZOLES AND THEIR USE AS PPARS ACTIVATORS | GLAXO GROUP LIMITED (GB) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102493-A1 | Thia-and oxazoles and their use as ppars activators | PPARA, PPARG, NCOA1 | PPARD 7/4885PPARA 1/4885PPARG 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.