Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12045326 | 0.83 | TP53 (0.71) | TP53KDM4ETSHRALDH1A1CYP11B1 | |
| Hydrochloric Acid SCHEMBL9996062 | 0.82 | TP53 (0.69) | TP53KDM4ETSHRALDH1A1CYP11B1 | |
| SCHEMBL5657503 | 0.80 | MEN1 (0.49) | TP53KDM4ETSHRALDH1A1CYP11B1 | |
| SCHEMBL5655020 | 0.78 | CYP19A1 (0.64) | TP53KDM4ETSHRALDH1A1CYP11B1 | |
| SCHEMBL4316370 | 0.75 | CYP11B1 (0.69) | CYP11B1CYP11B2CYP19A1KMT2ATBXAS1 | |
| SCHEMBL12045327 | 0.74 | TP53 (0.67) | TP53KDM4ETSHRALDH1A1CYP19A1 | |
| SCHEMBL76839 | 0.74 | KDM4E (0.72) | KDM4EALDH1A1MEN1KMT2ATBXAS1 | |
| Hydrochloric Acid SCHEMBL9996047 | 0.73 | TP53 (0.65) | TP53KDM4ETSHRALDH1A1CYP19A1 | |
| SCHEMBL6302835 | 0.73 | QPCT (0.73) | KDM4EMEN1KMT2ATBXAS1LMNA | |
| SCHEMBL6671107 | 0.73 | TP53 (0.74) | TP53KDM4ETSHRALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262185-B2 | Benzazepine derivative, process for producing the same, and use | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20040235822-A1 | Benzazepine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-11-25 | — | — | US | disclosed |
| EP-1422228-A1 | BENZAZEPINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Chemical Industries, Ltd. (JP) | 2004-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235822-A1 | Benzazepine derivative, process for producing the same, and use | CYP1B1, CYP1A1, CYP2E1 | TP53 4651/4885KDM4E 512/4885TSHR 2872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.