Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23043971 | 0.85 | GAA (0.42) | KCNH2GAABRD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL2638232 | 0.82 | KCNH2 (0.42) | KCNH2GAABRD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL15969910 | 0.82 | BRD4 (0.41) | KCNH2GAABRD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL27670108 | 0.81 | BRD4 (0.40) | KCNH2GAABRD4HTTSMN1; SMN2 | |
| Water SCHEMBL9893341 | 0.81 | BRD4 (0.40) | KCNH2GAABRD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL10147185 | 0.79 | KCNH2 (0.45) | KCNH2GAABRD4ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL5657547 | 0.79 | BRD4 (0.39) | KCNH2GAABRD4HTTSMN1; SMN2 | |
| SCHEMBL2647561 | 0.78 | — | — | |
| SCHEMBL8026054 | 0.77 | — | — | |
| SCHEMBL15740501 | 0.77 | KCNH2 (0.47) | KCNH2GAABRD4ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174903-B | Small molecule modulators of TLR8 | 清华大学 | 2022-07-12 | — | — | CN | disclosed |
| WO-2021000755-A1 | SMALL-MOLECULE REGULATOR OF TLR8 | 清华大学 | 2021-01-07 | — | — | WO | disclosed |
| CN-112174903-A | Small molecule modulators of TLR8 | 清华大学 | 2021-01-05 | — | — | CN | disclosed |
| WO-2020061375-A1 | ANTIBACTERIAL COMPOUNDS | FORGE THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| US-7262185-B2 | Benzazepine derivative, process for producing the same, and use | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20040235822-A1 | Benzazepine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-11-25 | — | — | US | disclosed |
| EP-1422228-A1 | BENZAZEPINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Chemical Industries, Ltd. (JP) | 2004-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235822-A1 | Benzazepine derivative, process for producing the same, and use | CYP1B1, CYP1A1, CYP2E1 | KCNH2 29/4885GAA 2987/4885BRD4 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.