⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butadiene SCHEMBL21219232 | 0.82 | — | — | |
| SCHEMBL27645077 | 0.78 | — | — | |
| Propene SCHEMBL1467613 | 0.78 | — | — | |
| Sulfuric Acid SCHEMBL29162142 | 0.78 | — | — | |
| Propene SCHEMBL29216590 | 0.75 | — | — | |
| Sulfuric Acid SCHEMBL11315657 | 0.75 | — | — | |
| Sulfuric Acid SCHEMBL11315660 | 0.75 | — | — | |
| Sulfuric Acid SCHEMBL11315664 | 0.75 | — | — | |
| Ethylene SCHEMBL1275306 | 0.75 | — | — | |
| SCHEMBL9540531 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1742009-A | Oxazolidinones as antibacterial agents | ASTRAZENECA AB (SE) | 2006-03-01 | — | — | CN | claimed |
| CN-102762574-B | Benzoxapi 3K inhibitor compounds and methods of use | HOFFMAN-LA ROCHE LTD. (CH) | 2015-12-02 | — | — | CN | disclosed |
| CN-104987345-A | BENZOXEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | HOFFMANN LA ROCHE | 2015-10-21 | — | — | CN | disclosed |
| CN-100390169-C | Hydroxymethyl substituted dihydroisoxazole derivatives useful as antibiotic agents | ASTRAZENECA AB (SE) | 2008-05-28 | — | — | CN | disclosed |
| CN-1989136-A | 3-[4-(6-{4, 5-dihydroisoxazol -3-yl} pyridin-3-yl)- 3-phenyl]-5 -(1h-1, 2, 3-triazol -1-ylmethyl)-1, 3-oxazolidin- 2-ones as antibacterial agents | ASTRAZENECA AB (SE) | 2007-06-27 | — | — | CN | disclosed |
| CN-1989135-A | 3- (4- (2-dihydroisoxazol-3-ylpyridin-5-yl) phenyl) -5-triazol-1-ylmethyloxazolidin-2-one derivaives as mao inhibitors for the treatment of bacterial infections | ASTRAZENECA AB (SE) | 2007-06-27 | — | — | CN | disclosed |
| US-7199143-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2007-04-03 | — | — | US | disclosed |
| CN-1753888-A | Hydroxymethyl substituted dihydroisoxazole derivatives useful as antibiotic agents | ASTRAZENECA AB (SE) | 2006-03-29 | — | — | CN | disclosed |
| CN-1742009-A | Oxazolidinones as antibacterial agents | ASTRAZENECA AB (SE) | 2006-03-01 | — | — | CN | disclosed |
| US-20050182112-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2005-08-18 | — | — | US | disclosed |
| CN-1653064-A | Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them | ASTRAZENECA AB (SE) | 2005-08-10 | — | — | CN | disclosed |