Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 20/20 | 0.55 |
| ▸ | ITGB2 | P05107 | 19/20 | 0.55 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4847515 | 1.00 | ITGAL (0.55) | ITGALITGB2ICAM1 | |
| SCHEMBL6772701 | 0.87 | ITGAL (0.51) | ITGALITGB2ICAM1 | |
| SCHEMBL14526231 | 0.85 | ITGAL (0.46) | ITGALITGB2ICAM1 | |
| SCHEMBL4841707 | 0.81 | ITGAL (0.55) | ITGALITGB2ICAM1 | |
| SCHEMBL4847241 | 0.81 | ITGAL (0.54) | ITGALITGB2ICAM1 | |
| SCHEMBL4840686 | 0.81 | ITGAL (0.54) | ITGALITGB2ICAM1 | |
| SCHEMBL4847530 | 0.80 | ITGAL (0.47) | ITGALITGB2ICAM1 | |
| SCHEMBL4847526 | 0.80 | ITGAL (0.47) | ITGALITGB2ICAM1 | |
| SCHEMBL4849044 | 0.80 | ITGAL (0.53) | ITGALITGB2ICAM1 | |
| SCHEMBL4849061 | 0.79 | ITGAL (0.52) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199125-B2 | Spiro-cyclic compounds useful as anti-inflammatory agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-03 | — | — | US | disclosed |
| US-7199125-B2 | Spiro-cyclic compounds useful as anti-inflammatory agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-03 | — | — | US | disclosed |
| US-7199125-B2 | Spiro-cyclic compounds useful as anti-inflammatory agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-03 | — | — | US | disclosed |
| US-20050119279-A1 | Spiro-cyclic compounds useful as anti-inflammatory agents | CEREP SA (FR) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119279-A1 | Spiro-cyclic compounds useful as anti-inflammatory agents | CCR9, MSR1, CCR3 | ITGAL 1187/4885ITGB2 2005/4885ICAM1 451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.