Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5660069 | 0.73 | KCNQ3 (0.34) | UHRF1CYP1A2CYP2A6 | |
| SCHEMBL5658747 | 0.70 | CYP1A2 (0.42) | UHRF1CYP1A2CYP2A6 | |
| SCHEMBL4718458 | 0.67 | CYP1A2 (0.42) | UHRF1CYP1A2CYP2A6 | |
| SCHEMBL14970161 | 0.66 | CYP1A2 (0.40) | UHRF1CYP1A2CYP2A6 | |
| SCHEMBL4715557 | 0.64 | UHRF1 (0.41) | UHRF1CYP1A2CYP2A6 | |
| SCHEMBL25669006 | 0.64 | — | — | |
| SCHEMBL10144238 | 0.63 | — | — | |
| SCHEMBL13727058 | 0.63 | — | — | |
| SCHEMBL3872583 | 0.62 | UHRF1 (0.46) | UHRF1CYP1A2CYP2A6 | |
| SCHEMBL2610402 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285563-B2 | Heteroaromatic urea derivatives as VR-1 receptor modulators for treating pain | MERCK SHARP & DOHME LTD. (GB) | 2007-10-23 | — | — | US | disclosed |
| US-20050107388-A1 | Heteroaromatic urea derivatives as vr-1receptor modulators for treating pain | MERCK SHARP & DOHME LTD. (GB) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107388-A1 | Heteroaromatic urea derivatives as vr-1receptor modulators for treating pain | ARRB1, OPRL1, CNR1 | UHRF1 1377/4885CYP1A2 464/4885CYP2A6 743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.