SCHEMBL5658804

SCHEMBL5658804

NC(CC(=O)O)C(=O)C(N)(Cc1ccccc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.64
HIF1A Q16665 1/20 0.64
ALPI P09923 1/20 0.42
PKM P14618 1/20 0.42
PTGS1 P23219 1/20 0.42
XIAP P98170 1/20 0.42
SLC7A5 Q01650 1/20 0.42
KIF11 P52732 8/20 0.41
SLC15A1 P46059 1/20 0.41
LTA4H P09960 3/20 0.40
CPA1 P15085 2/20 0.40
CPB1 P15086 1/20 0.40
CPA3 P15088 1/20 0.40
CPB2 Q96IY4 1/20 0.40
ARG1 P05089 1/20 0.38
ARG2 P78540 1/20 0.38
SLC6A2 P23975 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
SLC1A3 P43003 1/20 0.37
SLC1A2 P43004 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27431678 0.89 SMN1; SMN2 (0.62) SMN1; SMN2HIF1AALPIPKMPTGS1
SCHEMBL11020715 0.85 SMN1; SMN2 (0.49) SMN1; SMN2HIF1AALPIPKMPTGS1
Hydrochloric Acid SCHEMBL9019585 0.84 SMN1; SMN2 (0.47) SMN1; SMN2HIF1AALPIPKMPTGS1
SCHEMBL3151239 0.79 SMN1; SMN2 (1.00) SMN1; SMN2HIF1AALPIPKMPTGS1
SCHEMBL9653234 0.78 SMN1; SMN2 (0.64) SMN1; SMN2HIF1AALPIPKMPTGS1
SCHEMBL9618909 0.77 SMN1; SMN2 (0.54) SMN1; SMN2HIF1ACPA1CPB1CPA3
SCHEMBL10866164 0.77 SMN1; SMN2 (0.46) SMN1; SMN2HIF1AALPIPKMPTGS1
SCHEMBL27342313 0.77 SMN1; SMN2 (0.46) SMN1; SMN2HIF1AALPIPKMPTGS1
Hydrochloric Acid SCHEMBL27358212 0.76 SMN1; SMN2 (0.45) SMN1; SMN2HIF1AALPIPKMPTGS1
Hydrochloric Acid SCHEMBL9191561 0.76 SMN1; SMN2 (0.41) SMN1; SMN2HIF1AALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0297560-B1 Imides; a process for their production and a process for the production of dipeptides using them AJINOMOTO KK (JP) 1998-03-04 EP claimed
EP-0327030-B1 Method for producing alpha-aspartylphenylalanine derivatives AJINOMOTO KK (JP) 1995-01-25 EP claimed
US-4942255-A ISOMERIZATION WITH A BASIC COMPOUND IN AN ALCOHOLIC SOLVENT TO PREVENT PRECIPITATION OF SALTS AJINOMOTO CO., INC. (JP) 1990-07-17 US claimed
EP-0327030-A2 Method for producing alpha-aspartylphenylalanine derivatives AJINOMOTO CO., INC. (JP) 1989-08-09 EP claimed
EP-0297560-A2 Imides; a process for their production and a process for the production of dipeptides using them Ajinomoto Co., Inc. (JP) 1989-01-04 EP claimed
US-4730076-A REDUCTION OF CORRESPONDING N-HYDROXYMETHYL COMPOUND NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1988-03-08 US claimed
US-4673744-A IN ALCOHOL SOLVENT AJINOMOTO CO., INC. (JP) 1987-06-16 US claimed
JP-1258657-A None JP disclosed
JP-6172382-A None JP disclosed
CN-102864196-B Method for preparing alpha-aspartyl small peptide by dihydroorotic acid enzyme method NANJING UNIVERSITY OF TECHNOLOGY 2014-07-02 CN disclosed
CN-102864196-A Method for preparing alpha-aspartyl small peptide by dihydroorotic acid enzyme method NANJING UNIVERSITY OF TECHNOLOGY 2013-01-09 CN disclosed
EP-1380570-A4 PROCESS FOR PRODUCING N-FORMYLAMINO ACID AND UTILIZATION THEREOF AJINOMOTO KK (JP) 2006-09-27 EP disclosed
EP-0297560-B1 Imides; a process for their production and a process for the production of dipeptides using them AJINOMOTO KK (JP) 1998-03-04 EP disclosed
EP-0297560-A2 Imides; a process for their production and a process for the production of dipeptides using them Ajinomoto Co., Inc. (JP) 1989-01-04 EP disclosed
EP-0297560-A2 Imides; a process for their production and a process for the production of dipeptides using them Ajinomoto Co., Inc. (JP) 1989-01-04 EP disclosed
US-4673744-A IN ALCOHOL SOLVENT AJINOMOTO CO., INC. (JP) 1987-06-16 US disclosed
US-4673744-A IN ALCOHOL SOLVENT AJINOMOTO CO., INC. (JP) 1987-06-16 US disclosed
EP-0155165-A2 Process for introducing phosphinoyl groups into amino groups AJINOMOTO CO., INC. (JP) 1985-09-18 EP disclosed
US-4434097-A Process for the removal of the formyl group from N-formyl peptides and esters thereof PIERREL S.P.A. (IT) 1984-02-28 US disclosed
US-4017472-A Process for isolation of aspartyl dipeptide esters G. D. SEARLE & CO. (US) 1977-04-12 US disclosed