SCHEMBL566064

SCHEMBL566064

[CH2]c1cccc([N+](=O)[O-])c1[N+](=O)[O-]

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.59
GPR35 Q9HC97 2/20 0.59
TDP1 Q9NUW8 5/20 0.52
ALDH1A1 P00352 5/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
S100A4 P26447 2/20 0.44
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
PDE10A Q9Y233 1/20 0.40
PTPRC P08575 1/20 0.40
ERN1 O75460 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL27871172 0.84 TSHR (0.65) TSHRGPR35TDP1ALDH1A1SMN1; SMN2
Formaldehyde SCHEMBL27604396 0.84 TSHR (0.65) TSHRGPR35TDP1ALDH1A1SMN1; SMN2
SCHEMBL118464 0.84 TSHR (0.71) TSHRGPR35TDP1ALDH1A1SMN1; SMN2
SCHEMBL1926046 0.84 TSHR (0.71) TSHRGPR35TDP1ALDH1A1SMN1; SMN2
Fluoride SCHEMBL29099623 0.81 TSHR (0.68) TSHRGPR35TDP1ALDH1A1SMN1; SMN2
SCHEMBL7157907 0.81 TSHR (0.68) TSHRGPR35TDP1ALDH1A1SMN1; SMN2
SCHEMBL29669769 0.81 TSHR (0.68) TSHRGPR35TDP1ALDH1A1SMN1; SMN2
SCHEMBL28529002 0.81 TSHR (0.68) TSHRGPR35TDP1ALDH1A1SMN1; SMN2
SCHEMBL7157905 0.81 TSHR (0.68) TSHRGPR35TDP1ALDH1A1SMN1; SMN2
Ammonia Solution, Strong SCHEMBL27735242 0.81 TSHR (0.68) TSHRGPR35TDP1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 446 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240200070-A1 EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2024-06-20 US claimed
US-20240124910-A1 RIBOSOME-MEDIATED POLYMERIZATION OF NOVEL CHEMISTRIES NORTHWESTERN UNIVERSITY 2024-04-18 US claimed
US-11814621-B2 Expanding the chemical substrates for genetic code reprogramming NORTHWESTERN UNIVERSITY (US) 2023-11-14 US claimed
WO-2023049774-A1 GENETICALLY ENCODED AND EXOGENOUSLY TRIGGERED PROTEIN-PROTEIN LIGATION UNIVERSITY OF WASHINGTON (US) 2023-03-30 WO claimed
CN-115867648-A Extension of chemical substrates for genetic code reprogramming to include long chain carbons and cyclic amino acids 西北大学 2023-03-28 CN claimed
EP-4103734-A2 LONG CHAIN CARBON AND CYCLIC AMINO ACIDS SUBSTRATES FOR GENETIC CODE REPROGRAMMING Northwestern University (US) 2022-12-21 EP claimed
WO-2021221760-A2 EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING TO INCLUDE LONG CHAIN CARBON AND CYCLIC AMINO ACIDS NORTHWESTERN UNIVERSITY (US) 2021-11-04 WO claimed
US-20210230586-A1 Expanding the Chemical Substrates for Genetic Code Reprogramming BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, THE 2021-07-29 US claimed
WO-2020040840-A2 EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING NORTHWESTERN UNIVERSITY (US) 2020-02-27 WO claimed
CN-108140452-B Anisotropic conductive film and display device using the same 国都化学株式会社 2020-02-18 CN claimed
US-5359017-A Using an organoiron compound NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1994-10-25 US claimed
US-5192767-A Nonphytotoxic BASF AKTIENGESELLSCHAFT (DE) 1993-03-09 US claimed
EP-0511405-A1 CATIONICALLY POLYMERIZABLE ORGANIC MATERIAL COMPOSITION AND STABILIZATION OF SAID COMPOSITION NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1992-11-04 EP claimed
EP-0393893-A1 Sulfonium compound and polymerisation initator comprising the sulfonium compound as the main ingredient SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1990-10-24 EP claimed
EP-0206147-B1 PROCESS FOR THE PREPARATION OF 4,4'-DINITRODIBENZYLS BAYER AG (DE) 1990-02-28 EP claimed
EP-0301873-A2 2'-deoxy-5-fluorouridine derivatives TAIHO PHARMACEUTICAL CO., LTD. (JP) 1989-02-01 EP claimed
EP-0108039-B1 AMMONIUM STANNATES-(IV) CIBA-GEIGY AG (CH) 1989-01-25 EP claimed
EP-0109354-B1 BIOCIDALLY ACTIVE MIXTURE CIBA-GEIGY AG (CH) 1986-11-20 EP claimed
EP-0109354-A1 Biocidally active mixture CIBA-GEIGY AG (CH) 1984-05-23 EP claimed
EP-0108039-A2 Ammonium stannates-(IV) CIBA-GEIGY AG (CH) 1984-05-09 EP claimed