Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795453 | 1.00 | MCHR1 (0.43) | MCHR1KCNH2CYP2D6CYP11B2KDR | |
| SCHEMBL4847488 | 0.94 | MCHR1 (0.44) | MCHR1KCNH2CYP2D6 | |
| SCHEMBL5660528 | 0.94 | MCHR1 (0.44) | MCHR1KCNH2CYP2D6 | |
| SCHEMBL5663761 | 0.90 | MCHR1 (0.49) | MCHR1KCNH2CYP2D6KDR | |
| SCHEMBL5662998 | 0.90 | MCHR1 (0.45) | MCHR1KCNH2CYP2D6 | |
| SCHEMBL5663766 | 0.90 | MCHR1 (0.49) | MCHR1KCNH2CYP2D6KDR | |
| SCHEMBL5662992 | 0.90 | MCHR1 (0.45) | MCHR1KCNH2CYP2D6 | |
| SCHEMBL5662853 | 0.89 | MCHR1 (0.44) | MCHR1KCNH2CYP2D6CYP11B2KDR | |
| SCHEMBL5663029 | 0.89 | MCHR1 (0.47) | MCHR1KCNH2CYP2D6 | |
| SCHEMBL5663032 | 0.89 | MCHR1 (0.47) | MCHR1KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299062-A1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-27 | — | — | US | claimed |
| US-20070299062-A1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299062-A1 | Melanin concentrating hormone antagonists | MCHR1, MCHR2, MC4R | MCHR1 1/4885KCNH2 4254/4885CYP2D6 1658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.