Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.33 |
| ▸ | TUBB | P07437 | 4/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL566573 | 0.86 | HDAC1 (0.46) | HDAC1HDAC2HDAC6HDAC8HDAC11 | |
| SCHEMBL565896 | 0.84 | HDAC1 (0.47) | HDAC1HDAC2HDAC6HDAC8HDAC11 | |
| SCHEMBL1562367 | 0.76 | HDAC1 (0.64) | HDAC1HDAC2HDAC6HDAC8HDAC11 | |
| SCHEMBL566527 | 0.74 | HDAC1 (0.66) | HDAC1HDAC2HDAC6HDAC8HDAC11 | |
| SCHEMBL565950 | 0.72 | HDAC1 (0.48) | HDAC1HDAC2HDAC6HDAC8HDAC11 | |
| SCHEMBL564932 | 0.72 | GRM5 (0.33) | — | |
| SCHEMBL565940 | 0.70 | HDAC1 (0.57) | HDAC1HDAC2HDAC6HDAC8HDAC11 | |
| SCHEMBL13380524 | 0.69 | HDAC1 (0.56) | HDAC1HDAC2HDAC6HDAC8HDAC11 | |
| SCHEMBL1563065 | 0.69 | HDAC1 (0.61) | HDAC1HDAC2HDAC6HDAC8HDAC11 | |
| SCHEMBL564975 | 0.67 | HDAC1 (0.55) | HDAC1HDAC2HDAC6HDAC8HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181182-B2 | S1P receptors modulators | AKAAL PHARMA PTY LTD (AU) | 2015-11-10 | — | — | US | disclosed |
| US-20120034270-A1 | S1P Receptors Modulators | AKAAL PHARMA PTY LTD (AU) | 2012-02-09 | — | — | US | disclosed |
| EP-2344446-A1 | S1P RECEPTORS MODULATORS | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010042998-A1 | S1P RECEPTORS MODULATORS | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120034270-A1 | S1P Receptors Modulators | S1PR1, S1PR5, S1PR3 | HDAC1 1849/4885HDAC2 1755/4885HDAC6 2352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.