⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2394589 | 1.00 | — | — | |
| SCHEMBL1417 | 1.00 | — | — | |
| SCHEMBL5211752 | 0.74 | — | — | |
| SCHEMBL2884361 | 0.73 | — | — | |
| SCHEMBL4392795 | 0.73 | — | — | |
| SCHEMBL22658 | 0.70 | — | — | |
| SCHEMBL26335 | 0.70 | — | — | |
| SCHEMBL8163460 | 0.70 | TSHR (0.35) | — | |
| SCHEMBL2887142 | 0.70 | — | — | |
| SCHEMBL14955 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170209440-A1 | METHODS AND COMPOSITIONS FOR TREATING HIV-RELATED DISORDERS | CHDI FOUNDATION, INC. | 2017-07-27 | — | — | US | claimed |
| EP-3169684-A1 | METHODS AND COMPOSITIONS FOR TREATING HIV-RELATED DISORDERS | CHDI Foundation, Inc. (US) | 2017-05-24 | — | — | EP | claimed |
| CN-106715421-A | Methods and compositions for treating hiv-related disorders | CHDI基金会股份有限公司 | 2017-05-24 | — | — | CN | claimed |
| CN-104277043-B | One-dimensional organic semiconductor nanotube and its preparation method and application | INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2017-01-04 | — | — | CN | claimed |
| WO-2016011316-A1 | METHODS AND COMPOSITIONS FOR TREATING HIV-RELATED DISORDERS | CHDI FOUNDATION, INC. (US) | 2016-01-21 | — | — | WO | claimed |
| CN-104277043-A | One-dimensional organic semiconductor nanotube as well as preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2015-01-14 | — | — | CN | claimed |
| CN-114588157-A | Methods and compositions for treating HIV-related disorders | CHDI基金会股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| EP-3169684-B1 | COMBINATION OF KMO INHIBITOR 6-(3-CHLORO-4-CYCLOPROPOXYPHENYL)PYRIMIDINE-4-CARBOXYLIC ACID WITH ANTIVIRAL AGENT FOR TREATING HIV RELATED NEUROLOGICAL DISORDERS | CHDI FOUNDATION INC (US) | 2019-06-26 | — | — | EP | disclosed |
| US-10258621-B2 | Methods and compositions for treating HIV-related disorders | CHDI FOUNDATION, INC. (US) | 2019-04-16 | — | — | US | disclosed |
| US-20190038631-A1 | 6-AMINO-PURIN-8-ONE COMPOUNDS | GLAXOSMITHKLINE LLC | 2019-02-07 | — | — | US | disclosed |
| US-10117873-B2 | 6-amino-purin-8-one compounds | GLAXOSMITHKLINE LLC (US) | 2018-11-06 | — | — | US | disclosed |
| EP-3336089-A1 | PURINE DERIVATIVES FOR USE IN THE TREATMENT OF ALLERGIC, INFLAMMATORY AND INFECTIOUS DISEASES | GlaxoSmithKline LLC (US) | 2018-06-20 | — | — | EP | disclosed |
| US-20180117048-A1 | 6-AMINO-PURIN-8-ONE COMPOUNDS | GLAXOSMITHKLINE LLC | 2018-05-03 | — | — | US | disclosed |
| US-20110135671-A1 | PURINE DERIVATIVES FOR USE IN THE TREATMENT OF ALLERGIC, INFLAMMATORY AND INFECTIOUS DISEASES | GLAXOSMITHKLINE LLC (US) | 2011-06-09 | — | — | US | disclosed |
| EP-2324026-A1 | PURINE DERIVATIVES FOR USE IN THE TREATMENT OF ALLERGIC, INFLAMMATORY AND INFECTIOUS DISEASES | Smithkline Beecham Corporation (US) | 2011-05-25 | — | — | EP | disclosed |
| US-20100075995-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-03-25 | — | — | US | disclosed |
| WO-2010018133-A1 | PURINE DERIVATIVES FOR USE IN THE TREATMENT OF ALLERGIC, INFLAMMATORY AND INFECTIOUS DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 2010-02-18 | — | — | WO | disclosed |
| US-5166167-A | Fungicides | ROUSSEL UCLAF (FR) | 1992-11-24 | — | — | US | disclosed |
| EP-0509857-A1 | Alpha-methylene 5-thiazolo acetic acid derivatives, intermediates and process of preparation, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1992-10-21 | — | — | EP | disclosed |
| EP-0508901-A2 | Alpha-methylene-4-[(phenoxy)methyl)]5-thiazolacetic acid derivatives, process for their preparation, intermediates in this process, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1992-10-14 | — | — | EP | disclosed |