Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.92 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.92 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.92 |
| ▸ | PDE5A | O76074 | 1/20 | 0.92 |
| ▸ | CA1 | P00915 | 1/20 | 0.92 |
| ▸ | CA2 | P00918 | 1/20 | 0.92 |
| ▸ | HMGCR | P04035 | 1/20 | 0.92 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.92 |
| ▸ | LCK | P06239 | 1/20 | 0.92 |
| ▸ | FYN | P06241 | 1/20 | 0.92 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.92 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.92 |
| ▸ | CA6 | P23280 | 1/20 | 0.92 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.92 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.92 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.92 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.92 |
| ▸ | TST | Q16762 | 1/20 | 0.92 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.92 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.92 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5663969 | 1.00 | USP2 (0.92) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| SCHEMBL5665043 | 0.99 | USP2 (0.90) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| SCHEMBL5664497 | 0.99 | USP2 (0.90) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| SCHEMBL5664781 | 0.97 | USP2 (0.86) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| SCHEMBL5663975 | 0.96 | USP2 (0.88) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| SCHEMBL23630701 | 0.96 | USP2 (1.00) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| Tannic Acid SCHEMBL25066810 | 0.96 | USP2 (1.00) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| SCHEMBL23630709 | 0.96 | USP2 (1.00) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| Tannic Acid SCHEMBL22105299 | 0.96 | USP2 (1.00) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| Tannic Acid SCHEMBL21865640 | 0.96 | USP2 (1.00) | USP2MAPK1TMPRSS2PDE5ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1545554-A4 | METHODS AND COMPOSITIONS FOR TREATING DIABETES MELLITIS | UNIV OHIO (US) | 2006-06-14 | — | — | EP | disclosed |
| US-20060058243-A1 | Methods and compositions for treating diabetes mellitis | OHIO UNIVERSITY | 2006-03-16 | — | — | US | disclosed |
| EP-1545554-A1 | METHODS AND COMPOSITIONS FOR TREATING DIABETES MELLITIS | Ohio University (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004009094-A1 | METHODS AND COMPOSITIONS FOR TREATING DIABETES MELLITIS | OHIO UNIVERSITY (US) | 2004-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058243-A1 | Methods and compositions for treating diabetes mellitis | IAPP, GCG, MTPN | USP2 4592/4885MAPK1 1019/4885TMPRSS2 3455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.