⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167934 | 0.78 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL258962 | 0.75 | — | — | |
| SCHEMBL127462 | 0.75 | — | — | |
| SCHEMBL16196001 | 0.75 | — | — | |
| SCHEMBL1097587 | 0.75 | — | — | |
| SCHEMBL1098657 | 0.75 | — | — | |
| SCHEMBL6064611 | 0.73 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL13266324 | 0.73 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL590895 | 0.73 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL2039259 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101124199-A | 5-substituted-2-phenylamino-benzamides as MEK inhibiting substances | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2008-02-13 | — | — | CN | claimed |
| CN-1185211-C | Benzamide derivatives for the treatment of diseases caused by cytokines | ASTRA ZENECA LTD (SE) | 2005-01-19 | — | — | CN | claimed |
| CN-1170827-C | Benzofurylpyrone derivatives | ������������ʽ���� | 2004-10-13 | — | — | CN | claimed |
| CN-1481369-A | Substituted phenyluracils compound | �ݶ�ũ�����ѧ�ɷݹ�˾ | 2004-03-10 | — | — | CN | claimed |
| EP-0659839-B1 | Process for the preparation of pyrazolazo dyestuffs | BAYER AG (DE) | 2001-09-26 | — | — | EP | claimed |
| CN-1300278-A | Benzamide derivatives for the treatment of diseases caused by cytokines | ASTRA ZENECA LTD (SE) | 2001-06-20 | — | — | CN | claimed |
| CN-1299359-A | Benzofurylpyrone derivatives | TEIJIN LTD (JP) | 2001-06-13 | — | — | CN | claimed |
| US-5635534-A | 1-PHENYL-2-(2-PHENYLOXY OR THIO)-1-METHYLETHYL)AMINOETHANOL DERIVATIVES; ALDOSE REDUCTASE INHIBITORS; NONTOXIC; ANTIDIABETIC,-OBESITY,-LIPEMIC AND HYPOGLYCEMIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-06-03 | — | — | US | claimed |
| CN-1034497-C | Process for the preparation of aromatic aminoalcohol derivatives useful for the treatment of diabetes and obesity | SANKYO CO (JP) | 1997-04-09 | — | — | CN | claimed |
| EP-0543662-B1 | Aromatic amino-alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses | SANKYO CO (JP) | 1996-09-18 | — | — | EP | claimed |
| CN-1073428-A | Aromatic amino alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic use | SANKYO CO (JP) | 1993-06-23 | — | — | CN | claimed |
| EP-0543662-A2 | Aromatic amino-alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-05-26 | — | — | EP | claimed |
| CN-87104156-A | Benzo buprofezin derivate | — | 1987-12-16 | — | — | CN | claimed |
| CN-87104046-A | THIAZINONE DERIVATIVES | — | 1987-12-16 | — | — | CN | claimed |
| CN-105073715-A | Dihydropyridazine-3,5-dione derivative | CHUGAI PHARMACEUTICAL CO LTD | 2015-11-18 | — | — | CN | disclosed |
| CN-101522657-B | STAT3/5 activation inhibitor | OTSUKA PHARMACEUTICAL CO.,LTD. (JP) | 2014-10-15 | — | — | CN | disclosed |
| CN-103476756-A | 3-ureidoisoquinolin-8-yl derivatives | ACTELION PHARMACEUTICALS LTD | 2013-12-25 | — | — | CN | disclosed |
| CN-86102263-A | A kind of novel androstane-17's preparation | — | 1987-02-04 | — | — | CN | disclosed |
| EP-0008884-A1 | Derivatives of clavulanic acid, a process for their preparation and their compositions | BEECHAM GROUP PLC (GB) | 1980-03-19 | — | — | EP | disclosed |
| EP-0007717-A1 | Clavulanic acid derivatives, a process for their preparation, their use, and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1980-02-06 | — | — | EP | disclosed |