⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687564 | 0.73 | — | — | |
| SCHEMBL219064 | 0.67 | — | — | |
| SCHEMBL26521663 | 0.65 | — | — | |
| SCHEMBL441048 | 0.65 | — | — | |
| SCHEMBL19832 | 0.65 | — | — | |
| SCHEMBL12724949 | 0.65 | — | — | |
| SCHEMBL14256437 | 0.65 | — | — | |
| SCHEMBL28016966 | 0.63 | — | — | |
| SCHEMBL9433116 | 0.62 | — | — | |
| Methane SCHEMBL20422713 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2712367-B1 | DIRECT TRIFLUOROMETHYLATIONS USING TRIFLUOROMETHANE | UNIV SOUTHERN CALIFORNIA (US) | 2018-09-26 | — | — | EP | claimed |
| US-9334253-B2 | Direct trifluoromethylations using trifluoromethane | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2016-05-10 | — | — | US | claimed |
| US-20140066640-A1 | DIRECT TRIFLUOROMETHYLATIONS USING TRIFLUOROMETHANE | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-03-06 | — | — | US | claimed |
| WO-2012148772-A1 | DIRECT TRIFLUOROMETHYLATIONS USING TRIFLUOROMETHANE | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2012-11-01 | — | — | WO | claimed |
| EP-2712367-B1 | DIRECT TRIFLUOROMETHYLATIONS USING TRIFLUOROMETHANE | UNIV SOUTHERN CALIFORNIA (US) | 2018-09-26 | — | — | EP | disclosed |
| US-9334253-B2 | Direct trifluoromethylations using trifluoromethane | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2016-05-10 | — | — | US | disclosed |
| US-20140066640-A1 | DIRECT TRIFLUOROMETHYLATIONS USING TRIFLUOROMETHANE | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-03-06 | — | — | US | disclosed |
| WO-2012148772-A1 | DIRECT TRIFLUOROMETHYLATIONS USING TRIFLUOROMETHANE | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2012-11-01 | — | — | WO | disclosed |
| EP-1451199-A4 | MAGNESIUM MEDIATED PREPARATION OF FLUORINATED ALKYLSILANES | UNIV SOUTHERN CALIFORNIA (US) | 2006-04-26 | — | — | EP | disclosed |
| US-6803477-B2 | EFFICIENT PREPARATION OF TRIFLUOROMETHYL- AND DIFLUORO-METHYLSILANES USING MAGNESIUM MEDIATED REDUCTION OF CHLOROSILANES REACTING WITH TRI- AND DIFLUOROMETHYL SULFIDES, SULFOXIDES AND SULFONES; AUTOCATALYSIS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2004-10-12 | — | — | US | disclosed |
| EP-1451199-A2 | MAGNESIUM MEDIATED PREPARATION OF FLUORINATED ALKYLSILANES | University Of Southern California (US) | 2004-09-01 | — | — | EP | disclosed |
| US-20030153778-A1 | Magnesium mediated preparation of fluorinated alkyl silanes | UNIVERSITY OF SOUTHERN CALIFORNIA | 2003-08-14 | — | — | US | disclosed |
| WO-2003048033-A2 | MAGNESIUM MEDIATED PREPARATION OF FLUORINATED ALKYLSILANES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2003-06-12 | — | — | WO | disclosed |