⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245695 | 0.72 | — | — | |
| SCHEMBL5666866 | 0.72 | — | — | |
| SCHEMBL7754689 | 0.67 | — | — | |
| SCHEMBL4195727 | 0.67 | — | — | |
| SCHEMBL1169064 | 0.65 | — | — | |
| SCHEMBL4199885 | 0.63 | — | — | |
| Propionic Acid SCHEMBL30633878 | 0.63 | FFAR3 (0.53) | — | |
| Hydrochloric Acid SCHEMBL23478346 | 0.62 | — | — | |
| Fluoride SCHEMBL19458344 | 0.62 | — | — | |
| Bromide SCHEMBL19458438 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1545572-A4 | CONJUGATES ACTIVATED BY CELL SURFACE PROTEASES AND THERAPEUTIC USES THEREOF | DENDREON CORP (US) | 2006-04-12 | — | — | EP | disclosed |
| EP-1545572-A2 | CONJUGATES ACTIVATED BY CELL SURFACE PROTEASES AND THERAPEUTIC USES THEREOF | Dendreon Corporation (US) | 2005-06-29 | — | — | EP | disclosed |
| US-20040001801-A1 | Conjugates activated by cell surface proteases and therapeutic uses thereof | CORVAS INTERNATIONAL, INC. | 2004-01-01 | — | — | US | disclosed |
| WO-2002095007-A2 | CONJUGATES ACTIVATED BY CELL SURFACE PROTEASES AND THERAPEUTIC USES THEREOF | DENDREON SAN DIEGO LLC (US) | 2002-11-28 | — | — | WO | disclosed |