Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 17/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 15/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071135 | 0.95 | ITGAV (0.48) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL8313118 | 0.89 | ITGAV (0.59) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL1070634 | 0.87 | ITGAV (0.49) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL1070535 | 0.85 | ITGAV (0.50) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL1069186 | 0.85 | ITGAV (0.47) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL1071117 | 0.84 | ITGAV (0.61) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL1070532 | 0.84 | ITGAV (0.47) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL1069836 | 0.83 | ITGAV (0.49) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL1070528 | 0.83 | ITGAV (0.45) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL27580890 | 0.83 | ITGAV (0.45) | ITGAVITGB3ITGA2BITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423152-A4 | SIMULTANEOUS IMAGING OF CARDIAC PERFUSION AND A VITRONECTIN RECEPTOR TARGETED IMAGING AGENT | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2006-12-27 | — | — | EP | disclosed |
| EP-1423152-A2 | SIMULTANEOUS IMAGING OF CARDIAC PERFUSION AND A VITRONECTIN RECEPTOR TARGETED IMAGING AGENT | Bristol-Myers Squibb Pharma Company (US) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003013346-A2 | SIMULTANEOUS IMAGING OF CARDIAC PERFUSION AND A VITRONECTIN RECEPTOR TARGETED IMAGING AGENT | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2003-02-20 | — | — | WO | disclosed |