Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753938 | 0.87 | KMT2A (0.65) | KMT2AL3MBTL1POLBPKMPTPN1 | |
| Diphenylacetic Acid SCHEMBL38022 | 0.78 | SRC (0.62) | KMT2AL3MBTL1POLBMEN1GAA | |
| Diphenylacetic Acid SCHEMBL8513250 | 0.78 | SRC (0.62) | KMT2AL3MBTL1POLBMEN1GAA | |
| Diphenylacetic Acid SCHEMBL6852183 | 0.75 | SRC (0.59) | KMT2AL3MBTL1POLBMEN1GAA | |
| Diphenylacetic Acid SCHEMBL9750917 | 0.75 | SRC (0.59) | KMT2AL3MBTL1POLBMEN1GAA | |
| Diphenylacetic Acid SCHEMBL28446280 | 0.75 | SRC (0.59) | KMT2AL3MBTL1POLBMEN1GAA | |
| Diphenylacetic Acid SCHEMBL8411440 | 0.75 | SRC (0.59) | KMT2AL3MBTL1POLBMEN1GAA | |
| Diphenylacetic Acid SCHEMBL418537 | 0.75 | SRC (0.59) | KMT2AL3MBTL1POLBMEN1GAA | |
| Diphenylacetic Acid SCHEMBL9485695 | 0.75 | SRC (0.59) | KMT2AL3MBTL1POLBMEN1GAA | |
| Diphenylacetic Acid SCHEMBL30803718 | 0.75 | SRC (0.59) | KMT2AL3MBTL1POLBMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471923-A4 | AMIDO MACROLIDES | KOSAN BIOSCIENCES INC (US) | 2006-01-11 | — | — | EP | disclosed |
| EP-1471923-A1 | AMIDO MACROLIDES | Kosan Biosciences, Inc. (US) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003061671-A1 | AMIDO MACROLIDES | KOSAN BIOSCIENCES, INC. (US) | 2003-07-31 | — | — | WO | disclosed |