⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL4910341 | 0.87 | — | — | |
| Dimethylamine SCHEMBL29462048 | 0.79 | KDM4E (0.38) | — | |
| Carbon Tetrachloride SCHEMBL28079634 | 0.72 | — | — | |
| Dimethylamine SCHEMBL28874924 | 0.72 | — | — | |
| Dimethylamine SCHEMBL13695986 | 0.71 | — | — | |
| Carbon Tetrachloride SCHEMBL3648805 | 0.71 | — | — | |
| SCHEMBL3824257 | 0.71 | — | — | |
| Dimethylamine SCHEMBL392668 | 0.71 | — | — | |
| Dimethylamine SCHEMBL1030 | 0.71 | — | — | |
| Dimethylamine SCHEMBL12415750 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113025000-A | PEDOT (Poly ethylene terephthalate) PSS (Poly styrene sulfonate) material, processing method and quantum dot light-emitting diode | TCL集团股份有限公司 | 2021-06-25 | — | — | CN | claimed |
| US-20170240489-A1 | SEPARATION PROCESS FOR C8 AROMATICS MIXTURE | SULZER MANAGEMENT AG (CH) | 2017-08-24 | — | — | US | claimed |
| JP-8311007-A | — | — | None | — | — | JP | disclosed |
| CN-109153674-B | Iminothiadiazine dioxide derivatives as inhibitors of plasmepsin V of plasmodium | UCB生物制药有限责任公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-108290860-B | Iminotetrahydropyrimidinone derivatives as PLASMEPSIN V inhibitors | UCB生物制药有限责任公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-113025000-A | PEDOT (Poly ethylene terephthalate) PSS (Poly styrene sulfonate) material, processing method and quantum dot light-emitting diode | TCL集团股份有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-108290860-A | Imino group tetrahydropyrimidine ketone derivatives as PLASMEPSIN V inhibitor | UCB生物制药私人有限公司 | 2018-07-17 | — | — | CN | disclosed |
| US-20070213355-A1 | 1H-Imidazo[4,5-C]Quinoline Derivatives in the Treatment of Protein Kinase Dependent Diseases | CAPRARO HANS-GEORG | 2007-09-13 | — | — | US | disclosed |
| EP-1501826-B1 | SUBSTITUTED INDOLES AS ALPHA-1 AGONISTS | HOFFMANN LA ROCHE (CH) | 2006-09-27 | — | — | EP | disclosed |
| EP-1689747-A1 | 1H-IMIDAZO [4,5-C] QUINOLINE DERIVATIVES IN THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES | Novartis AG (CH) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005054238-A1 | 1H-IMIDAZO[4,5-C]QUINOLINE DERIVATIVES IN THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES | NOVARTIS AG (CH) | 2005-06-16 | — | — | WO | disclosed |
| US-6852726-B2 | Substituted indoles as alpha-1 agonists | SYNTEX LLC (US) | 2005-02-08 | — | — | US | disclosed |
| EP-1501826-A2 | SUBSTITUTED INDOLES AS ALPHA-1 AGONISTS | F. Hoffman-la Roche AG (CH) | 2005-02-02 | — | — | EP | disclosed |
| US-20030220319-A1 | Substituted indoles as alpha-1 agonists | SYNTEX (U.S.A.) LLC | 2003-11-27 | — | — | US | disclosed |
| WO-2003064387-A2 | SUBSTITUTED INDOLES AS ALPHA-1 AGONISTS | F. HOFFMAN-LA ROCHE AG (CH) | 2003-08-07 | — | — | WO | disclosed |
| JP-H08311007-A | AZULENE-1-CARBOXAMIDINE DERIVATIVE | TAISHO PHARMACEUT CO LTD | 1996-11-26 | — | — | JP | disclosed |
| US-4313931-A | ANTIHISTAMINES, ANTISEROTONINE AGENTS, ANTIALLERGENS, BRONCHODILATOR AGENTS, ANTIANAPHYLACTIC AGENTS | BOEHRINGER INGELHEIM KG (DE) | 1982-02-02 | — | — | US | disclosed |