Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.55 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PLD2 | O14939 | 2/20 | 0.33 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652029 | 1.00 | MAPK14 (0.55) | MAPK14MAPK11TDO2BUB1ALDH1A1 | |
| SCHEMBL5650860 | 0.93 | MAPK14 (0.54) | MAPK14MAPK11BUB1 | |
| SCHEMBL5665333 | 0.93 | MAPK14 (0.54) | MAPK14MAPK11BUB1 | |
| SCHEMBL5646091 | 0.93 | MAPK14 (0.56) | MAPK14MAPK11BUB1ALOX5 | |
| SCHEMBL5649551 | 0.92 | MAPK14 (0.53) | MAPK14MAPK11SMN1; SMN2 | |
| SCHEMBL5665739 | 0.92 | MAPK14 (0.53) | MAPK14MAPK11SMN1; SMN2 | |
| SCHEMBL5667585 | 0.92 | MAPK14 (0.55) | MAPK14MAPK11BUB1 | |
| SCHEMBL5651554 | 0.92 | MAPK14 (0.55) | MAPK14MAPK11BUB1 | |
| SCHEMBL5665083 | 0.90 | MAPK11 (0.58) | MAPK14MAPK11ALOX5 | |
| SCHEMBL5650805 | 0.90 | MAPK11 (0.58) | MAPK14MAPK11ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070049620-A1 | Cyclic tertiary amine compound | SANKYO COMPANY, LIMITED (JP) | 2007-03-01 | — | — | US | disclosed |
| EP-1632488-A1 | CYCLIC TERTIARY AMINE COMPOUND | Sankyo Company, Limited (JP) | 2006-03-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049620-A1 | Cyclic tertiary amine compound | MYD88, IL5, BRD4 | MAPK14 467/4885MAPK11 520/4885TDO2 2631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.