Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.60 |
| ▸ | PPARA | Q07869 | 8/20 | 0.59 |
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669729 | 0.95 | PPARD (0.62) | PPARDPPARAPPARG | |
| SCHEMBL5669274 | 0.87 | PPARD (0.65) | PPARDPPARAPPARG | |
| SCHEMBL5669664 | 0.86 | PPARD (0.55) | PPARDPPARAPPARG | |
| SCHEMBL5669961 | 0.84 | PPARD (0.50) | PPARDPPARAPPARG | |
| SCHEMBL3533093 | 0.81 | PPARD (0.55) | PPARDPPARAPPARG | |
| SCHEMBL1375925 | 0.80 | PPARD (0.62) | PPARDPPARAPPARG | |
| SCHEMBL5507055 | 0.79 | PPARD (0.74) | PPARDPPARAPPARG | |
| SCHEMBL377375 | 0.79 | PPARD (0.74) | PPARDPPARA | |
| SCHEMBL1549661 | 0.79 | PPARD (0.71) | PPARDPPARA | |
| SCHEMBL12646846 | 0.79 | PPARD (0.80) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682508-A1 | PHENYL DERIVATIVES AS PPAR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005049573-A1 | PHENYL DERIVATIVES AS PPAR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-06-02 | — | — | WO | disclosed |