SCHEMBL5667653

SCHEMBL5667653

C=C(C(=O)OCC(F)(F)C(F)F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
POLB P06746 2/20 0.36
GAA P10253 1/20 0.36
ALDH1A1 P00352 4/20 0.35
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
NPSR1 Q6W5P4 3/20 0.35
LMNA P02545 2/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12939550 0.86 POLB (0.31) TSHRPOLBGAAALDH1A1LMNA
SCHEMBL9578242 0.84 TSHR (0.34) TSHRPOLBGAAALDH1A1MEN1
SCHEMBL2526807 0.82 TSHR (0.37) TSHRPOLBGAAALDH1A1MEN1
SCHEMBL14112060 0.81 HTT (0.34) HTT
SCHEMBL227643 0.81 TSHR (0.47) TSHRPOLBGAAALDH1A1MEN1
SCHEMBL7169915 0.81 TSHR (0.39) TSHRPOLBGAAALDH1A1MEN1
SCHEMBL4397557 0.79 TSHR (0.40) TSHRPOLBGAAALDH1A1MEN1
SCHEMBL942139 0.79 HTT (0.46) HTT
SCHEMBL20624824 0.79 MAPK1 (0.33) ALDH1A1MAPK1HTT
SCHEMBL3408391 0.79 TSHR (0.37) TSHRGAANPSR1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569323-B2 Resist protective coating material and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-04 US disclosed
US-20070026341-A1 Resist protective coating material and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-02-01 US disclosed
US-20060178457-A1 Optical members and polymerizable compositions and thio compounds for producing them FUJIFILM CORPORATION (JP) 2006-08-10 US disclosed
EP-0541395-B1 Coating agents TAKEMOTO OIL & FAT CO LTD (JP) 1996-05-08 EP disclosed
US-5501904-A POLYSILOXANE-VINYL GRAFT POLYMER TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 1996-03-26 US disclosed
US-5405691-A Polysiloxane-polyvinyl graft copolymer TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 1995-04-11 US disclosed
EP-0541395-A1 Coating agents Takemoto Yushi Kabushiki Kaisha (JP) 1993-05-12 EP disclosed