Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.54 |
| ▸ | PPARA | Q07869 | 5/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669862 | 0.95 | PPARD (0.53) | PPARDPPARAPPARGESR1 | |
| SCHEMBL5673680 | 0.88 | PPARD (0.51) | PPARDPPARAPPARG | |
| SCHEMBL5668123 | 0.86 | PPARD (0.51) | PPARDPPARAPPARGESR1 | |
| SCHEMBL1550306 | 0.86 | PPARD (0.48) | PPARDPPARAPPARG | |
| SCHEMBL5669274 | 0.85 | PPARD (0.65) | PPARDPPARAPPARG | |
| SCHEMBL1548974 | 0.83 | PPARD (0.59) | PPARDPPARAPPARG | |
| SCHEMBL5667677 | 0.82 | PPARD (0.51) | PPARDPPARAESR1 | |
| SCHEMBL1550141 | 0.82 | PPARD (0.53) | PPARDPPARAPPARGESR1 | |
| SCHEMBL5669982 | 0.81 | PPARD (0.47) | PPARDPPARAPPARG | |
| SCHEMBL1549441 | 0.81 | PPARA (0.42) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682508-A1 | PHENYL DERIVATIVES AS PPAR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005049573-A1 | PHENYL DERIVATIVES AS PPAR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-06-02 | — | — | WO | disclosed |