SCHEMBL5669222

SCHEMBL5669222

Cc1oc(Oc2cccc(Br)c2)nc1CN(Cc1ccc(OC(C)(C)C(=O)O)cc1)Cc1nccn1C

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 18/20 0.60
PPARG P37231 17/20 0.60
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5484427 0.92 PPARA (0.51) PPARAPPARGKDM4EMAPT
SCHEMBL14414944 0.87 PPARA (0.80) PPARAPPARG
SCHEMBL14414942 0.80 PPARA (0.67) PPARAPPARG
SCHEMBL5669226 0.78 PPARG (0.51) PPARAPPARG
SCHEMBL5481550 0.75 PPARA (0.89) PPARAPPARG
SCHEMBL5483538 0.74 PPARA (0.85) PPARAPPARG
Hydrochloric Acid SCHEMBL5669569 0.73 PPARA (0.84) PPARAPPARG
SCHEMBL5668334 0.73 PPARA (0.80) PPARAPPARG
SCHEMBL5484463 0.73 PPARA (0.87) PPARAPPARG
SCHEMBL14414941 0.73 PPARA (0.80) PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1731513-A1 PHENOXYACETIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-12-13 EP disclosed