SCHEMBL5669477

SCHEMBL5669477

CCSC(C)C(=O)Oc1ccc(C#N)cc1NC(=O)C1(CCC(C)C)CCCCC1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CETP P11597 18/20 0.61
USP21 Q9UK80 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1899253 0.83 CETP (0.65) CETPUSP21
SCHEMBL1524499 0.76 CETP (1.00) CETP
SCHEMBL1898634 0.71 CETP (0.63) CETP
SCHEMBL1896736 0.70 CETP (0.63) CETP
SCHEMBL1898874 0.68 CETP (0.64) CETP
SCHEMBL1899968 0.68 CETP (0.48) CETP
SCHEMBL1525616 0.66 CETP (0.63) CETP
SCHEMBL993460 0.66 CETP (0.76) CETP
SCHEMBL1902078 0.66 CETP (0.63) CETP
SCHEMBL1524009 0.66 CETP (0.86) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670446-A2 METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION JAPAN TOBACCO INC. (JP) 2006-06-21 EP claimed
WO-2005030185-A2 METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION JAPAN TOBACCO INC. (JP) 2005-04-07 WO claimed
EP-1670446-A2 METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION JAPAN TOBACCO INC. (JP) 2006-06-21 EP disclosed
WO-2005030185-A2 METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION JAPAN TOBACCO INC. (JP) 2005-04-07 WO disclosed