SCHEMBL5669503

SCHEMBL5669503

O=C(O)c1cccc(C#Cc2ccccc2)c1-c1c(C#Cc2ccccc2)cccc1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.61
RAB9A P51151 1/20 0.61
HNF4A P41235 2/20 0.50
ALDH1A1 P00352 6/20 0.46
ALOX15 P16050 1/20 0.46
AKR1C2 P52895 1/20 0.46
AKR1C1 Q04828 1/20 0.46
KDM4E B2RXH2 3/20 0.46
MAPT P10636 2/20 0.46
HPGD P15428 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MEN1 O00255 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 1/20 0.46
LMNA P02545 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16719414 0.91 NPC1 (0.56) NPC1RAB9AHNF4AALDH1A1ALOX15
SCHEMBL2256468 0.86 NPC1 (0.72) NPC1RAB9AHNF4AALDH1A1ALOX15
SCHEMBL29479413 0.86 NPC1 (0.72) NPC1RAB9AHNF4AALDH1A1ALOX15
SCHEMBL16720829 0.85 NPC1 (0.49) NPC1RAB9AHNF4AALDH1A1ALOX15
SCHEMBL16720597 0.85 NPC1 (0.49) NPC1RAB9AHNF4AAKR1C2AKR1C1
SCHEMBL18125276 0.85 MYC (0.54) NPC1RAB9AHNF4AALDH1A1KDM4E
SCHEMBL38694 0.84 NPC1 (0.59) NPC1RAB9AHNF4AALDH1A1ALOX15
SCHEMBL16719808 0.83 GRM5 (0.51) NPC1RAB9AHNF4AALDH1A1AKR1C2
SCHEMBL30607509 0.82 NPC1 (0.67) NPC1RAB9AHNF4AALDH1A1ALOX15
SCHEMBL16719486 0.82 FABP3 (0.49) NPC1RAB9AHNF4AAKR1C2AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed