SCHEMBL5669606

SCHEMBL5669606

O[C@H](CN(CCc1cc(C(F)(F)F)ccc1F)c1cccc(Oc2ccnc(C(F)(F)F)c2)c1)C(F)(F)F

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 19/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL993072 0.92 CETP (0.67) CETP
SCHEMBL993089 0.92 CETP (0.67) CETP
SCHEMBL993146 0.86 CETP (0.67) CETP
SCHEMBL993112 0.86 CETP (0.67) CETP
SCHEMBL7091253 0.85 CETP (0.63) CETP
SCHEMBL6568890 0.82 CETP (0.69) CETP
SCHEMBL5671890 0.81 CETP (0.54) CETP
SCHEMBL5669610 0.80 CETP (0.48) CETP
SCHEMBL993706 0.80 CETP (0.63) CETP
SCHEMBL992953 0.80 CETP (0.63) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670446-A2 METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION JAPAN TOBACCO INC. (JP) 2006-06-21 EP claimed
WO-2005030185-A2 METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION JAPAN TOBACCO INC. (JP) 2005-04-07 WO claimed