Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.35 |
| ▸ | PPM1D | O15297 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5671908 | 0.83 | F10 (0.46) | F10SMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL5570807 | 0.79 | TSHR (0.41) | SMN1; SMN2MEN1KMT2AHTTGAA | |
| SCHEMBL5672352 | 0.69 | F10 (0.64) | F10 | |
| SCHEMBL5670109 | 0.68 | F10 (0.61) | F10SMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL3429653 | 0.67 | F10 (0.50) | F10SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL3429658 | 0.67 | F10 (0.50) | F10SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL5669867 | 0.67 | F10 (0.64) | F10KMT2AHTTGAAALDH1A1 | |
| SCHEMBL27711838 | 0.65 | SMN1; SMN2 (0.53) | F10SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL27711835 | 0.65 | SMN1; SMN2 (0.53) | F10SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL3428540 | 0.65 | F10 (0.63) | F10SMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628668-A2 | 1,1-DISUBSTITUTEDCYCLOALKYL-, GLYCINAMIDYL-, SULFONYL-AMIDINO-, AND TETRAHYDROPYRIMIDINYL-CONTAINING DIAMINOALKYL, BETA-AMINOACIDS, ALPHA-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITO RS | Bristol-Myers Squibb Company (US) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004108892-A2 | 1,1-DISUBSTITUTEDCYCLOALKYL-, GLYCINAMIDYL-, SULFONYL-AMIDINO-, AND TETRAHYDROPYRIMIDINYL-CONTAINING DIAMINOALKYL, β-AMINOACIDS, α-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-16 | — | — | WO | disclosed |