Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 8/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995174 | 0.90 | SLC6A2 (0.51) | CETPSLC6A2SLC6A4PAX8ALDH1A1 | |
| SCHEMBL5672347 | 0.89 | CETP (0.45) | CETPSLC6A2SLC6A4EPHX1LMNA | |
| SCHEMBL993039 | 0.84 | SLC6A2 (0.44) | CETPSLC6A2SLC6A4PAX8ALDH1A1 | |
| SCHEMBL992714 | 0.79 | CETP (0.55) | CETP | |
| SCHEMBL1901252 | 0.79 | CETP (0.52) | CETPSLC6A2SLC6A4LMNAKMT2A | |
| SCHEMBL993148 | 0.77 | CETP (0.59) | CETP | |
| SCHEMBL1897349 | 0.76 | CETP (0.53) | CETPSLC6A2SLC6A4 | |
| SCHEMBL1896263 | 0.75 | SLC6A2 (0.50) | SLC6A2SLC6A4 | |
| SCHEMBL7782487 | 0.75 | SLC6A2 (0.38) | CETPSLC6A2SLC6A4LMNA | |
| SCHEMBL1900062 | 0.75 | CETP (0.58) | CETPSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670446-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2006-06-21 | — | — | EP | claimed |
| WO-2005030185-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | WO | claimed |