SCHEMBL5670641

SCHEMBL5670641

CCCCCCCCCCCCCCCCCC(SS)[Si](C)(C)OC

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.34
LMNA P02545 2/20 0.33
DNM1 Q05193 2/20 0.32
SMPD1 P17405 3/20 0.32
OPRM1 P35372 1/20 0.31
TSHR P16473 1/20 0.31
THRB P10828 1/20 0.31
FDPS P14324 3/20 0.31
GPR84 Q9NQS5 2/20 0.31
SPHK1 Q9NYA1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5670636 0.90 ZDHHC7 (0.35) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL5671816 0.85 ZDHHC7 (0.34) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL5669706 0.85 ZDHHC7 (0.34) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL8827116 0.83 ZDHHC7 (0.33) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL8826328 0.83 ZDHHC7 (0.33) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL8827223 0.81 ZDHHC7 (0.33) ZDHHC7LMNADNM1SMPD1
SCHEMBL8826552 0.81 ZDHHC7 (0.33) ZDHHC7LMNADNM1SMPD1
SCHEMBL8826703 0.81 ZDHHC7 (0.33) ZDHHC7LMNADNM1SMPD1
SCHEMBL8826921 0.81 ZDHHC7 (0.33) ZDHHC7LMNADNM1SMPD1
SCHEMBL5669699 0.76 ZDHHC7 (0.36) ZDHHC7LMNADNM1SMPD1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0995775-B1 Preparation of stach reinforced rubber, vulcanized rubber tire and article of manufacture GOODYEAR TIRE & RUBBER (US) 2004-08-18 EP claimed
EP-0994150-B1 Preparation of reinforced rubber GOODYEAR TIRE & RUBBER (US) 2004-03-24 EP claimed
US-6458871-B2 MIXING A ORGANOSILANE DISULFIDE, A RUBBER AND A REINFORCING FILLER THE GOODYEAR TIRE & RUBBER COMPANY 2002-10-01 US claimed
US-6384127-B2 MIXTURE CONTAINING ORGANOSILANE DISULFIDE COMPOUND THE GOODYEAR TIRE & RUBBER COMPANY 2002-05-07 US claimed
US-20020019473-A1 SILICA REINFORCED RUBBER COMPOSITION AND USE IN TIRES GOODYEAR TIRE & RUBBER COMPANY, THE 2002-02-14 US claimed
US-20010034392-A1 Preparation of reinforced rubber and use in tires THE GOODYEAR TIRE & RUBBER COMPANY 2001-10-25 US claimed
US-20010031803-A1 Preparation of starch reinforced rubber and use thereof in tires THE GOODYEAR TIRE & RUBBER COMPANY 2001-10-18 US claimed
US-6156822-A Prepared reinforced elastomer, elastomer composite and tire having component thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-12-05 US claimed
EP-1002835-A2 Reinforced elastomer preparation and tire having component thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-05-24 EP claimed
EP-1002836-A1 Method for preparing in-situ-reinforced elastomer THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-05-24 EP claimed
EP-1000960-A1 Preparation of reinforced elastomer THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-05-17 EP claimed
EP-0995775-A1 Preparation of starch reinforced rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-04-26 EP claimed
EP-0994150-A1 Preparation of reinforced rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-04-19 EP claimed
EP-0732362-B1 Silica reinforced rubber composition and use in tyres GOODYEAR TIRE & RUBBER (US) 1999-06-02 EP claimed
EP-0845493-A1 Silica reinforced rubber composition and use in tires THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-06-03 EP claimed
US-5580919-A ORGANOSILANE DISULFIDE COUPLER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-12-03 US claimed
EP-0732362-A1 Silica reinforced rubber composition and use in tyres THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-09-18 EP claimed
EP-1293529-B1 Elastomer/reinforcing filler composite GOODYEAR TIRE & RUBBER (US) 2006-12-13 EP disclosed
US-5580919-A ORGANOSILANE DISULFIDE COUPLER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-12-03 US disclosed
EP-0732362-A1 Silica reinforced rubber composition and use in tyres THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-09-18 EP disclosed